3Iregui M, Ward S, Sherman G, et al. Clinical importance of delays in the initiation of appropriate antibiotic treatment for ventilator - associated pneumonia[ J]. Chest, 2002, 122( 1 ) : 262 -268.
4Vincent JL, Moreno R, Takala J, et al. The SOFA ( sepsis related organ failure assessment) score to describe organ dysfunction/failure. Intensive Care Med, 1996, 22(7) : 707 -710.
5Gao F, Melody T, Daniels DF, et al. The impact of compliance with 6 - hour and 24 - hour sepsis bundles on hospital mortality in patients with severe sepsis : a prospective observational study [ J ]. Crit Care, 2005,9(6) : R764 - R770.
6Rivers E, Nguyen B, Havstad S, et al. Early good - directed therapy in the treatment of severe sepsis and septic shock[J]. N Engl J Med, 2001,345 (19) : 1368 - 1377.
7Astiz ME, DeGent GE, Lin RY, et al. Microvaseular function and rheologic changes in hyperdynamic sepsis[ J]. Crit Care Med, 1995, 23(2) :265 -271.
8Alsous F, Khamiees M, DeGirolamo A, et al. Negative fluid balance predicts survival in patients with septic shock: a retrospective pilot study[J]. Chest, 2000, 117(6) : 1749 - 1754.
9Shoemaker WC, Appel PL, Kram HB, et al. Sequence of physiologic patterns in physiology in surgical septic shock [ J ]. Crit Care Med, 1993, 21(12) : 1876 -1889.