摘要
目的:探讨早期非小细胞肺癌(non-small cell lung cancer,NSCLC)患者的淋巴结清扫范围。方法:回顾分析2005年—2008年561例肿瘤最大径≤5 cm的cN0NSCLC患者的临床资料。所有患者均行肺叶切除及系统性淋巴结清扫术,比较不同肺叶肿瘤的纵隔淋巴结转移部位的情况。结果:在271例上肺叶肿瘤中,上纵隔淋巴结转移37例(13.7%),隆突下淋巴结转移8例(3.0%),下纵隔淋巴结转移2例(0.7%);在217例下肺叶肿瘤中,隆突下淋巴结转移的20例(9.2%),上纵隔淋巴结转移的11例(5.1%)。结论:肺叶特异性淋巴结清扫对于早期NSCLC患者是一种合理的淋巴结处理策略。
Objective:To investigate the optimal range of nodal dissection in early-stage non-small cell lung cancer(NSCLC). Methods:From 2005 to 2008, 561 patients with NSCLC of less than 5 cm in the diameter of tumor and NO stage underwent sur- gery with systematic nodal dissection (SND). N2 disease was revealed histologically after surgery and patterns of lymph nodal metastasis was analyzed. Results: Among 271 patients with upper lobe tumors, superior mediastinal lymph nodes metastases were found in 37 patients (13.7%), whereas subcarinal metastases were found in 8 patients (3.0%), and inferior mediastinal involvements were found in only 2 patients (0.7%). Among 217 patients with lower lohe tumors, subcarinal involvements were found in 20 patients (9.2%), whereas superior mediastinal metastases were found in only 11 patients (5.1%). Conclu- sion: Lobe-specific SND might be an effective and appropriate strategy for patients with early-stage NSCLC.
出处
《中国临床医学》
2012年第6期616-618,共3页
Chinese Journal of Clinical Medicine
关键词
肺肿瘤
癌
淋巴结清扫术
Lung neoplasm Carcinoma Lymph node dissection