摘要
[目的]探讨预防全髋关节置换术围手术期深静脉血栓形成的有效措施。[方法]设立前瞻性对照研究,自2010年1月～2011年12月,将收治的256例拟行全髋关节置换术的病例随机分配在实验组(接受下肢静脉泵和低分子肝素钠注射)和对照组(接受活血药物,下肢静脉泵和低分子肝素钠注射),观察两组中病例在围手术期的深静脉血栓发生率。[结果]因股骨颈骨折接受全髋关节置换术的病例较因股骨头坏死及髋关节发育不良而接受全髋关节置换术的病例发生深静脉血栓的概率高(P<0.05);合并肺部疾病和糖尿病的患者较合并高血压的患者发生深静脉血栓的概率高(P<0.05);应用活血药物的病例组深静脉血栓的发生率无明显降低;应用下肢静脉泵和低分子肝素注射的病例组深静脉血栓发生概率降低。[结论]年龄>70岁且合并糖尿病和肺部疾病是高危因素;术前应用活血药物不能降低深静脉血栓的发生率;应用低分子肝素和下肢静脉泵能明显降低全髋关节置换术病例发生深静脉血栓的概率。
[ Objective] To explore the effective ways to prevent the occurrence of deep vein thrombosis （DVT） in the pa- tients undergoing total hip arthroplasty （THA）. [ Method ] In this prospective study from January 2010 to December 2011,256 cases of patients who underwent THA were randomized into two groups. The patients in trial group underwent application of dressing vein pump and low molecular weight heparin（LMWH）. The patients in control group underwent medicine to modulate the dynamics of blood, application of dressing vein pump and LMWH. The occurrence of DYT was documented. [ Result ] The occurrence of DVT in the patients with femoral neck fracture, pulmonary disorders and diabetes was higher than that in the pa- tients with high blood pressure （P 〈 0.05 ）. The application of medicine to modulate the dynamics of blood did not influence the occurrence of DVT. The occurrence of DVT was lower in the patients underwent application of dressing vein pump and LMWH. [ Conclusion ]The high risk factors of involving DVT in the patients underwent THA included age 〉 70 years, accompanied with pulmonary disorders and diabetes. The application of medicine to modulate the dynamics of blood was not useful to decrease the occurrence of DVT. The application of LMWH and dressing vein pump were effective to decrease the occurrence of DVT in the patients underwent THA.
出处
《中国矫形外科杂志》
CAS
CSCD
北大核心
2013年第4期350-353,共4页
Orthopedic Journal of China
