摘要
【目的】观察不同高压氧(hyperbaric oxygen,HBO)治疗方法改善脑外伤觉醒障碍患者的近期疗效指标。【方法】连续选择近年来我院住院治疗脑外伤觉醒障碍患者65例,入选对象均接受了HBO治疗,压力为0.22MPa,稳定吸氧时间为60min,1～2次/d,6～12次/周,共治疗4周。并按不同HBO治疗方法分组:(1)按治疗频次分组:多频次组(治疗2次/d,29例)和少频次组(治疗1次/d,36例)。(2)按接受治疗时间分组:早期治疗组(10d内接受治疗,35例)和晚期治疗组(10d后接受治疗,30例)。治疗前后接受了Glasgow昏迷量表评分(Glasgow coma scale,GCS)、脑外伤残疾评分量表评分(Disabiliti raying scale,DRS)测评。【结果】多频次治疗组和早期治疗组的平均昏迷天数和平均住院天数均明显低于少频次治疗组和晚期治疗组(P均<0.01)。多频次治疗组和早期治疗组治疗后GCS和DRS评分均明显优于治疗前,同时也优于少频次治疗组和晚期治疗组(P<0.05或P<0.01)。【结论】HBO治疗频次多和早期接受HBO治疗对脑外伤觉醒障碍患者的促醒作用和近期疗效指标均较为明显。
[Objective]To observe the indexes for recent therapeutic effect of the different methods of hyperbaric oxygen （HBO） therapy on improving patients with traumatic brain injury accompanied by arousal disorders.[Methods]Sixty-five patients with traumatic brain injury accompanied by arousal disorders, who were treated in hospital in recent years, were successively selected. All the enrolled subjects accepted the HBO therapy, the pressure was 0.22 MPa, and the stable oxygen uptake duration was 60 min/time, once or twice a day, and 6～12 times/week for a total of 4 weeks. The subjects were grouped according to the different HBO therapeutic methods： （1）grouping by therapeutic frequency： more frequency group （twice a day, n = 29） and fewer frequency group （twice a day, n =36）. （2）grouping by therapeutic time： early therapy group （accepted therapy within 10 days, n = 35） and late therapeutic group （accepted therapy after 10 days, n = 30）. All the patients were evaluated with the Glasgow Coma Scale （GCS） before and after therapy, respectively.[Results]The average days of coma and average length of stay in the more frequency group and early therapy group were obviously lower than those in the fewer frequency group and late therapeutic group （P 0.01）. The scores of GSC and DRS in the more frequency group and early therapy group after therapy were obviously better than those before therapy, and were also better than those in the fewer frequency group and late therapeutic group （ P 0.05～0.01）.[Conclusion]Early HBO therapy at more frequencies has more obvious influence on accelerating arousal and on the indexes for the recent therapeutic effect in patients with traumatic brain injury accompanied by arousal disorders.
出处
《武警后勤学院学报（医学版）》
CAS
2012年第12期952-954,共3页
Journal of Logistics University of PAP（Medical Sciences）
关键词
脑外伤
觉醒障碍
高压氧治疗
频次
开始治疗时间
近期疗效指标
Traumatic brain injury/arousal disorders
Hyperbaric oxygen therapy
Frequency
Start time of therapy
Indexes for recent therapeutic effect
