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急诊应用胺碘酮治疗快速型室上性心律失常疗效观察 被引量:9

Amiodarone in emergency treatment of fast supraventricular arrhythmia
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摘要 目的探讨急诊应用胺碘酮治疗快速型室上性心律失常的临床疗效。方法按入院先后顺序,80例室上性心律失常患者被随机分为对照组与观察组(n=40)。对照组:心律平70mg+生理盐水20ml,5~10min缓慢静推,继而以0.5~1mg/min持续静滴,复律成功者继续口服心律平片150mg,3次/d;观察组:胺碘酮150mg+生理盐水20ml,时间5~10min缓静推,继之以0.5~1.0mg/min持续静滴,复律成功者继续口服胺碘酮片0.29mg,1次/d。观察24h内两组患者转复率和不良反应。结果观察组的转复率85.0%(34/40)高于对照组70%(28/40),组间比较差异有统计学意义(P<0.05);无严重不良反应,组间比较差异无统计学意义(P>0.05)。结论胺碘酮急诊治疗快速型室上性心律失常转复率高,且不增加不良反应,是急诊治疗该病的首选药物。 Objective To explore the effect of amiodarone in emergency treatment of fast supraventricular arrhythmia.Methods By admission sequencing,80 cases of supraventricular arrhythmia patients were randomly divided into a control group and the observation group(n=40).Control group: the propafenone 70mg + saline 20ml,5~10min slow bolus,then in 0.5-lmg/min continuous intravenous infusion,cardioversion Winners oral propafenone tablets 150mg,3 times / d;observation group: amiodarone150mg + saline 20ml,5~10min slow bolus followed by 0.5~1.0mg/min continuous infusion cardioversion successful oral amiodarone tablets 0.29mg,1 times/d.The two groups were observed within 24h emergency cardioversion efficient and adverse reaction.Results Cardioversion rate of the observation group(85.0%) was higher than that of the control group(70%),the difference was statistically significant between groups(P0.05);no serious adverse reactions,the difference between groups was not statistically significant(P0.05).Conclusions Amiodarone for fast supraventricular arrhythmia effect on the better is the drug of choice for emergency treatment of the disease.
作者 罗毅
出处 《齐齐哈尔医学院学报》 2012年第24期3354-3355,共2页 Journal of Qiqihar Medical University
关键词 快速性 心律失常 胺碘酮 心律平 治疗应用 Speedability supraventricular Arrhythmia Amiodarone Propafenone
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