摘要
目的:探讨儿童阻塞性睡眠呼吸暂停低通气综合征(OSAHS)对儿童生长发育的影响。方法:选择符合OSAHS诊断标准的53例儿童作为治疗组,进行扁桃体切除术和(或)腺样体切除术治疗,同时选择51例正常儿童作为对照组。观察治疗组手术前后PSG的主要指标,测定治疗组患儿手术前后血浆中生长激素(GH)的含量及对照组儿童血浆中GH的含量,准确记录治疗组患儿的身高和体重,并与对照组儿童的身高和体重进行比较。结果:与手术前比较,治疗组儿童PSG的各项指标中血氧饱和度上升(P<0.05),其他指标下降(P<0.05)。治疗组术前GH含量低于对照组,两组比较差异有统计学意义(P<0.05);术后3个月GH含量升高,与对照组比较差异无统计学意义。治疗组术前身高和体重较对照组低,差异均有统计学意义(P<0.05)。结论:OSAHS患儿因上呼吸道梗阻,严重影响睡眠质量,导致GH分泌下降,身高、体重受到影响,应尽早采取手术干预措施。
Objective：To investigate the influence of obstructive sleep apnea hypopnea syndrome（OSAHS） on children＇s growth.Method：Fifty-three children diagnosed as OSAHS were included in the treatment group and underwent tonsillectomy or adenoidectomy,and 51 normal children were employed as the control group.Main data monitered by PSG and growth hormone（GH） in children of the treatment group were recorded before and after surgery,in addition,growth hormone,height and weight of children in the treatment group and control group were respectively recorded and compared.Result：Height and weight of children with OSAHS before treatment were lower than that of the normal children and the difference was significant（P0.05）.Compared with the data before surgery,oxygen saturation of blood in children of treatment group recorded by PSG increased（P0.05）, while value of other data decreased（P0.05）.Growth hormone in children of the treatment group was lower than that of the control group and the difference between two group was significant（P0.05）,while the content of growth hormone in children of the treatment group elevated after 3months postoperatively and at this time no difference was found between the two groups.Conclusion：Children with OSAHS present the symptom of upper airway obstruction,which badly affects sleep quality and results in decreased secretion of growth hormone and finally the height and weight of children is got involved.Timely surgery is necessary to alleviate the symptom.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2013年第4期209-211,共3页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
