摘要
目的了解心、肝功能在三氯乙烯药疹样皮炎(DMLT)病程过程中的变化情况,为临床治疗提供依据。方法检测不同病程阶段ALT、AST、LDH、α-HBDH、CK和CK-MB水平,同时对患者心、肝、胆、脾等脏器进行B超检查和心电图检查。结果所有酶水平均呈逐渐下降趋势,且三期数据相比有显著性差异(P<0.01)。但急性期CK水平明显降低,与初期及恢复期比较差异显著(P<0.01)。B超显示,发病初期和急性期患者肝、胆、脾脏多呈现不同程度的病理性改变,恢复期多数正常。结论 ALT、心肌酶、B超检查可作为DMLT机体损伤严重程度的评价指标及治疗效果的检测指标。
Objective To provide the proves for treatment of dermatitis medicamentosa-like of trichloroethylene（DMLT） pa- tients by analyzing the changes of cardiac and hepatic function. Methods The index of ALT,AST,LDH,α-HBDH,CK and CK-MB were detected at different courses of disease,and then the differences were analyzed. At the same time,B ultrasound examination of cardiac,hepatic,gallbladder and spleen and ECG were performed. Results Levels of all enzymes had a gradual downward trend in case group,with significant difference between early stages, acute phase and convalescence（P〈 0.01）. Compared with the early stage and convalescence,CK level in acute phase was significantly decreased（P〈0.01）. Conclusion ALT level,myocardial enzymes and B ultrasound might be useful evaluation indexes of injury severity in DMLT and the treatment effect.
出处
《国际检验医学杂志》
CAS
2013年第3期307-308,共2页
International Journal of Laboratory Medicine
基金
深圳市科技计划项目(201002139)
国家重点职业病临床专科项目
关键词
三氯乙烯
药疹
肝功能试验
心脏功能试验
：trichloroethylene
drug eruptions
liver function tests
heart function tests
