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超声造影引导下915MHz微波经皮凝固实验犬肝动脉及门脉损伤的止血研究

Contrast ultrasound guided 915 MHz microwave percutaneous coagulation therapy of the hepatic artery and portal vein injury in vivo experiment
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摘要 目的评价915MHz微波经皮凝固肝动脉及门脉损伤的活体实验效果。方法制造肝动脉及门脉损伤模型后,分别行超声造影引导下915MHz微波经皮凝固治疗与药物注射治疗,比较两者的止血效果、出血量与病理结果。结果915MHz微波经皮肝动脉及门脉损伤的止血效果优于药物注射,出血量明显小于注射法,病理结果显示血管壁坏死及周围组织凝固改变较注射法明显。结论超声造影引导下915MHz微波具有明显的止血作用,经皮凝固肝动脉及门脉损伤的犬活体实验具有重要的临床辅助意义。 Objective To evaluate the hemostasis effect of 915 MHz microwave in the hepatic artery and portal vein injury in vivo dog liver. Methods After manufactured model of the hepatic artery and portal vein injury,915MHz microwave percutaneous coagulation therapy and drug injections were performed under the guidance of contrast-enhanced ultrasound (CEUS), the hemostatic effect, amount of bleeding and histologic findings were compared between the two groups. Results 915 MHz microwave coagulation had better hemostatic effect than drug injection,the amount of bleeding was significantly less than the injection method, and the pathological results showed that the vessel wall necrosis and surrounding tissue coagulation were more obvious than the injection. Conclusions CEUS guided 915 MHz microwave has a significant role in hemostasis, so the 915 MHz microwave percutaneous coagulation therapy of the hepatic artery and portal vein injury in vivo dog liver has important clinical auxiliary significance.
出处 《中华超声影像学杂志》 CSCD 北大核心 2013年第1期75-79,共5页 Chinese Journal of Ultrasonography
基金 国家自然科学基金(30825010) 中国国际合作项目(2006DFA32300)
关键词 超声检查 微气泡 微波 治疗应用 止血 Ultrasonography Microbubbles Microwave/therapeutic use Hemostasis
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参考文献14

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