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腺病毒为载体的新型结核病疫苗Ad5Ag85A 被引量:2

Adenoviral vector based new tuberculosis vaccine Ad5Ag85A
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摘要 结核病是一个在全球范围内严重威胁人类健康的呼吸道传染性疾病。据世界卫生组织(WHO)估计,世界上约有1/3的人口受到结核分枝杆菌(Mycobacterium tuberculosis)的感染,其中1/10的人可能会最终患上结核病。全球每年的新病例超过900万,约200万人死于结核病[1]。
出处 《中华微生物学和免疫学杂志》 CAS CSCD 北大核心 2013年第1期73-78,共6页 Chinese Journal of Microbiology and Immunology
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参考文献35

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  • 2World Health Organization. Global Tuberculosis Control:Epidemiology,Strategy,Financing[M].Geneva:World Health Organization,2009.
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二级参考文献8

  • 1张钰,黄韧.结核病研究中的非人灵长类感染模型[J].中国比较医学杂志,2006,16(1):45-48. 被引量:1
  • 2Barclay WR, Busey WM, Dalgard DW, et al. Protection of monkeys against airborne tuberculosis by aerosol vaccination with bacillus Calmette Guerin[J]. Am Rev Respir Dis, 1973, 107:351-358.
  • 3Sugawara I, Sun L, Mizuno S. Protective effcacy of recombinant BCG Tokyo (Ag85A) in rhesus monkeys (Maeaca mulatta) infected intratracheally with H37Rv Mycobacterium tuberculosis [J]. Tuberculosis, 2009, 89 : 62-67.
  • 4Walsh GP, Tan EV, dela Cruz EC, et al. The Philippine cynomolgus monkey (Macaca fasicularis) provides a new nonhuman primate model of tuberculosis that resembles human disease[J]. Nat Med,1996,2:430-436.
  • 5Barclay WR, Anacker RL, Brehmer W, et al. Aerosolinduced tuberculosis in subhuman primates and the course of the disease after intravenous BCG vaccination [J]. Infect Immun, 1970, 2(5):574-582.
  • 6Capuano SV 3rd, Croix DA, Pawar S, et al. Experimental mycobacterium tuberculosis infection of cynomolgus macaques closely resembles the various manifestations of human M. tuberculosis infection[J]. Infect Immun, 2003, 71(10): 5 831-5 844.
  • 7中华人民共和国国家质量监督检验检疫总局.GB14922.1-2001,实验动物寄生虫学等级及监测[s].北京:中国标准出版社,2001:1-5.
  • 8中华人民共和国国家质量监督检验检疫总局.GB14922.2-2001,实验动物微生物学等级及监测[s].北京:中国标准出版社,2001:6-12.

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