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鼠骨髓间充质干细胞诱导的成骨细胞与3-羟基丁酸/3-羟基己酸共聚物的体外相容性 被引量：3

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摘要 目的探讨SD大鼠骨髓间充质干细胞(BMSCs)诱导的成骨细胞与3-羟基丁酸/3-羟基己酸共聚物(PHBHHx)支架材料的体外相容性,进一步验证PHBHHx材料作为骨组织工程支架材料的可行性。方法将SD大鼠BMSCs诱导的成骨细胞与PHBHHx支架材料体外复合培养,通过扫描电镜观察细胞与材料的复合情况,用MTT法检测材料对细胞增殖的影响。结果成骨细胞在PHBHHx支架材料表面及孔隙中能较好地黏附和增殖。结论 PHBHHx与成骨细胞有良好的体外相容性,是一种性能优良的骨组织工程支架材料。
作者 马敏先 周祥文 王永 王梅
机构地区 贵阳医学院附属医院口腔修复科 合肥医学院附属口腔医院修复科
出处 《中国老年学杂志》 CAS CSCD 北大核心 2013年第3期614-616,共3页 Chinese Journal of Gerontology
基金 贵州省科学技术基金(黔科合J字〔2010〕2177号)
关键词 骨髓间充质干细胞 成骨细胞 3-羟基丁酸/3-羟基己酸共聚物(PHBHHx) 体外相容性
分类号 R783.1 [医药卫生—口腔医学]
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参考文献8

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二级参考文献8

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共引文献11

同被引文献51

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中国老年学杂志
2013年 第3期

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