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大肠癌术后应用卡培他滨联合奥沙利铂治疗的不良反应护理体会 被引量:6

Colorectal Postoperative Capecitabine Gemcitabine Plus Oxaliplatin Treatment Nursing Experience Adverse Reactions
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摘要 目的:探讨大肠癌患者术后应用卡培他滨联合奥沙利铂化疗不良反应的护理对策。方法:对32例卡培他滨联合奥沙利铂治疗大肠癌术后患者所致不良反应进行相应护理。结果:32例患者共完成192周期化疗,不良反应主要表现为周围神经毒性、手足综合征、消化道反应、骨髓抑制等,多数为Ⅰ度或Ⅱ度,经对症处理及护理后缓解,顺利度过化疗期,生活自理。结论:恰当有效的护理措施可以预防或减轻不良反应的发生,确保化疗顺利进行。 Objective:To investigate patients with colorectal cancer postoperative capecitabine gemcitabine plus oxaliplatin chemotherapy adverse reactions nursing strategy.Method:32 cases of capecitabine and oxaliplatin in colorectal cancer patients due to adverse reactions accordingly care.Result:32 patients completed a total of 192 cycles of chemotherapy,adverse reactions mainly peripheral neurotoxicity,hand-foot syndrome,gastrointestinal reactions,bone marrow suppression,most Ⅰ or Ⅱ remission after symptomatic treatment and care to survive the chemotherapy period of daily living.Conclusion:The appropriate and effective care measures to prevent or mitigate adverse events,to ensure the smooth progress of chemotherapy.
出处 《中国医学创新》 CAS 2012年第36期95-96,共2页 Medical Innovation of China
关键词 卡培他滨 奥沙利铂 化疗 不良反应 护理 Capecitabine Oxaliplatin Chemotherapy Adverse reactions Nursing care
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  • 1黄素萍,叶文琴,王筱慧.应用多瑞吉治疗中重度癌痛患者的护理[J].中华护理杂志,2004,39(3):229-230. 被引量:15
  • 2陈文振,黄韬.胆汁癌胚抗原的检测与结肠癌肝转移的关系初探[J].临床外科杂志,2005,13(4):251-252. 被引量:3
  • 3[1]Blum JL, Jones SE, Buzdar AU, et al. Multicenter phase Ⅱ study of capecitabine in paclitaxel-refractory metastatic breast cancer. J Clin Oncol, 1999, 17 (2):485
  • 4[2]Talbot DC, Moiseyenko V, Van Belle S, et al. Randomised,phase Ⅱ trial comparing oral capecitabine (Xeloda) with paclitaxel in patients with metastatic/advanced breast cancer pretreatedwith anthracyclines. Br J Cancer, 2002, 86 (9):1367
  • 5[3]Meta-analysis goup in cancer. Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced coleorectal cancer. J Clin Oneol. 1998, 16:301
  • 6[4]Meta-analysis group in carcer. Toxicity of fiuorouracil in patients with advanced colorectal cancer: Effect of administration schedule and prognostic factors. J Clin Oncol, 1998, 16:3537
  • 7[5]Lokich JJ, Moore C. Chemotherapy-associated palmar-plantar erythrodysesthesia syndrome. Ann Inter Med, 1984, 101 :798
  • 8[6]Blum JL, Jones SE, Buzdar AU, et al. Multicenter phase Ⅱ study of capecitabine in paclitaxel-refractory metastatic breast cancer. J Clin Oncol, 1999, 17 (2) :485
  • 9[7]Vukelja SJ, Lombardo FA, James WD, et al. Pyridoxine for the palar-plantar erythrodysesthesia syndrome. Ann Inter Med,1989, 111:688
  • 10[8]Fabian CJ, Molina R, Slavik M, et al. Pyridoxine therapy for palmar-plantar erythrodysesthesia associated with continuous 5-fluorouracil infusion. Invest New Drugs, 1990, 8:57

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  • 1孙福香.静脉化疗药物的输注方法对疗效及副作用的影响[J].中国实用护理杂志(中旬版),2006,22(2):55-56. 被引量:9
  • 2Bokemeyer C,Bondarenko I,Makhson A. Fluo-rouracil,leucovorin,and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorec-tal cancer[J].{H}Journal of Clinical Oncology,2009,(75):663-671.
  • 3Jensen SA,Baeksgaard L,Petersen LN. Cardiotoxic-ity induced by 5-fluorouracil or capecitabine][J].{H}Ugeskrift for Laeger,2010,(01):48.
  • 4Gastaminza G,de la Borbolla JM,Goikoetxea MJ. A new rapid desensitization protocol for chemotherapy agents[J].J Investig Allergol Clin Im-munol,2011,(02):108-112.
  • 5Syrigou EI,Karapanagiotou EM,Alamara CV. Hy-persensitivity reactions to oxaliplatin:a retrospective study and the development of a desensitization protocol[J].Clin Colorectal Cancer,2009,(02):106-109.
  • 6Vaccaro AR, Lehman RA Jr, Hurlbert RJ,et al. A newclassification of thoracolumbar injuries : the importance of injurymorphology,the integrity of the posteriorligamentous complex, andneurologic status[ J]. Spine,2005,30(20) :2325-2333.
  • 7Verlann JJ,Diekerhof CH,Buskens E,et al. Surgical treatment oftraumatic fractures of the thoracic and lumbar spine : a systematicreview of the literature ontechniques, complications,and outcome[J]. Spine,2004,29(7) :803-814.
  • 8张玉红.奥沙利铂联合氟尿嘧啶治疗肠道肿瘤毒副反应的观察及护理[J].全科护理,2009,7(9):753-754. 被引量:6
  • 9孔秋焕,刘玉珊,吕林华.奥沙利铂联合卡培他滨治疗晚期或复发性结直肠癌的护理[J].全科护理,2010,8(4):287-288. 被引量:7
  • 10董梅,邢镨元,刘鹏,冯奉仪,石远凯.钙镁制剂和谷胱甘肽预防奥沙利铂所致神经毒性的效果观察[J].中华肿瘤杂志,2010,32(3):208-211. 被引量:46

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