摘要
目的探讨结肠癌多发肝转移瘤行肝动脉介入治疗的效果。方法选择我院2006年1月～2009年1月收治的结直肠癌多发肝转移患者共86例,按治疗方法分为两组,肝动脉介入组46例采用肝动脉化疗栓塞治疗,全身静脉化疗组40例采用全身静脉化疗,观察两组患者的近期疗效以及12、24、36个月的生存率。结果肝动脉介入组有效率与全身静脉化疗组比较,差异有高度统计学意义(P<0.01);肝动脉介入组12、24、36个月总生存率高于全身静脉化疗组,差异有统计学意义(P<0.05);两组患者各项不良反应比较差异无统计学意义(P>0.05)。结论与全身静脉化疗比较,肝动脉介入治疗对结肠癌术后肝转移有较好疗效。
Objective To discuss the effectiveness of artery interventional therapy in colon cancer patients with multiple liver metastases.Methods 86 cases of colon cancer with multiple liver metastases from January 2006 to January 2009 in our hospital were collected and divided into two groups,46 cases in hepatic artery interventional chemotherapy group were treated with hepatic artery interventional chemotherapy,40 cases in intravenous chemotherapy group were received with intravenous chemotherapy.Short term effect,survival rates of 12,24,36 months were recorded and analyzed.Results The difference of effective rate between the hepatic artery interventional chemotherapy group and intravenous chemotherapy group was statistically significant（P 0.05）;the survival rate of 12,24,36 months in hepatic artery interventional chemotherapy group were higher than those in intravenous chemotherapy group,the differences were statistically significant（P 0.05）;the difference of adverse reaction between the two groups was not statistically significant（P 0.05）.Conclusion Compared with the intravenous chemotherapy,the hepatic artery interventional chemotherapy for colon cancer patients with multiple liver metastases has a better effect,can offer patients an extended survival.
出处
《中国医药导报》
CAS
2013年第1期67-68,75,共3页
China Medical Herald
关键词
结肠癌
多发
肝转移
肝动脉
介入治疗
Colon carcinoma
Multiple
Liver metastases
Hepatic artery
Interventional therapy
