摘要
目的研究孟鲁司特钠干预治疗法对于小儿支原体肺炎(MPP)的临床疗效。方法将本院2009年1月～2011年1月收治的74例小儿MPP患儿随机分为实验组与对照组各37例,对照组使用抗生素与平喘化痰退热药物,实验组在对照组的基础上加用孟鲁司特钠进行干预治疗。比较两组患儿退热时间与咳嗽停止时间,此外于治疗2周后行X线摄片与血清学检查并进行比较。结果实验组患儿的平均退热时间为(5.42±0.91)d,喘息停止时间为(5.81±1.13)d,咳嗽停止时间为(9.67±1.05)d,对照组分别为(5.85±1.17)、(8.52±1.57)与(13.34±2.08)d,其差异具有统计学意义(P<0.05)。此外实验组X线显示阴影消散者为20例,抗体滴度转阴者26例,对照组分别为15例与19例,两者差异具有统计学意义(P<0.05)。结论孟鲁司特钠对小儿MPP的干预治疗拥有良好的疗效,其可以减少患儿的发热时间,尽早使患儿停止咳喘,在临床上具有一定的推广意义。
Objective To study the clinical efficacy of montelukast sodium intervention therapy for Mycoplasma pneumonia （MPP）. Methods Seventy-four cases of children with MPP admitted to our hospital from January 2009 to January 2011 were randomly divided into the experimental group and the control group, within each got 37 cases. The control group used antibiotics and asthma phlegm antipyretic drugs, while the experimental group plused montelukast sodium intervention on the basis of the control group. The fever clearance time and the cough stop time of each group as well as the result of X-ray radiography and serological examination after 2 weeks of treatment were compared. Results The average cooling time of the experimental group patients was （5.42±0.91） d, wheezing stop time was （5.81±1.13） d, coughing stop time was （9.67±1.05） d, the counterpart of control group were （5.85±1.17）, （8.52±1.57） and （13.34± 2.08） d, the difference was statistically significant （P 0.05）. In addition, X-ray of the experimental group showed the shadows dissipated by 20 cases, negative antibody titers were 26 patients while the counterpart of control group were 15 cases and 19 cases, both with significant differences （P 0.05）. Conclusion Montelukast sodium intervention has a good effect on the treatment of MPP, which can reduce the heating time of the children, as early as possible the children stop coughing promote the significance of certain clinical.
出处
《中国当代医药》
2013年第2期74-75,共2页
China Modern Medicine
关键词
孟鲁司特钠
小儿支原体肺炎
咳嗽
临床疗效
Montelukast sodium
Mycoplasma pneumonia in children
Cough
Clinical efficacy
