期刊文献+

凯力康治疗急性脑梗死患者的血液流变学指标变化 被引量:2

暂未订购
导出
摘要 目的探讨凯力康治疗急性脑梗死的临床疗效与对血液流变学指标的影响。方法选取我院神经内科2011年1月~2012年8月收治的急性脑梗死住院患者70例,随机分为两组分别以凯力康与依达拉奉治疗。结果观察组治疗后总有效率为94.3%,对照组治疗后的总有效率为82.9%,观察组患者痊愈率、总有效率均显著高于对照组(P<0.05)。两组患者治疗后全血黏度、血浆粘度、血细胞压积、纤维蛋白原含量均比治疗前明显改善(P<0.05),观察组患者全血黏度、血浆粘度、纤维蛋白原含量改善情况与对照组相比明显较好(P<0.05),两组血细胞压积改善情况无显著差异(P>0.05)。结论凯力康治疗急性脑梗死具有疗效显著的特点,能够有效改善血液流变情况,具有较高的临床价值。
出处 《中国现代药物应用》 2013年第1期68-69,共2页 Chinese Journal of Modern Drug Application
  • 相关文献

参考文献3

二级参考文献16

  • 1龚浠平.尤瑞克林改善脑血管储备能力的研究[J].中国卒中杂志,2007,2(6):545-548. 被引量:77
  • 2丁德云,吕传真,丁美萍,苏炳华,陈峰.人尿激肽原酶治疗急性脑梗死多中心随机双盲安慰剂对照试验[J].中华神经科杂志,2007,40(5):306-310. 被引量:169
  • 3Nagano H, Suzuki T, Nakamura S, et al. Pharmacological studies onhuman urinary kallidinogenase(SK-827):cerebral protective effects[J]. Yakugaku Zasshi, 1993,113( 11 ) : 803-809.
  • 4Emanueli C, Madeddu P. Angiogruesis therapy with human tissuekallikrein for the treatment of ischemic diseases[J]. Arch MalCoeur, 2004,97 (6) : 679-687.
  • 5Xia CF,Yin H,Borlongan CV,et al. Kallikrein gene transferprotects against ischemic stroke by promoting glial cell migration and ilnhibiting apoptosis[J]. Hypertension, 2004,43 (2) : 452-459.
  • 6全国第四次脑血管病学术会议.脑卒中患者临床功能缺损程度评分标准.中华神经科杂志,1995,:381-382.
  • 7Chao J, ChaoL. Experimental against cerebral ischemia [J].1327. therapy with tissue kallikrein Front Biosci, 2006,11 : 1323.
  • 8Gao G, Shao C, Zhang S X, et al. Kallikrein-binding protein inhibits retinal neovascularization and decreases vascular leakage [J]. Diabetologia, 2003,46 (5) : 689-698.
  • 9Chao J, Bledsoe G, Yin H, et al. The tissue kallikrein-kinin system protects against cardiovascular and renal diseases and ischemic stroke independently of blood pressure reduction [J]. Biol Chem,2006,387(6) : 665-675.
  • 10Lu HS,Lin FK,Chao L,et al.Human Urinarykallikrein:Complete Amino Acid Sequence and Sites of Glycosylation [J].Int J Pept Protein Res, 1989,33(4):237-249.

共引文献9

同被引文献41

  • 1张晓举,李颢.缺血性脑卒中患者超敏C反应蛋白及白细胞介素6测定及临床意义[J].中国医药导报,2005,2(24):7-8. 被引量:7
  • 2中风病诊断与疗效评定标准(试行)[J].北京中医药大学学报,1996,19(1):55-56. 被引量:6363
  • 3刘清阁,边连防,陈晓红,伍爱民.脑梗死急性期血清IL-6、IL-8动态变化及其与脑梗死病情、预后的相关研究[J].中国医师进修杂志(内科版),2006,29(9):28-30. 被引量:22
  • 4Camerlingo M,Valente L,Tognozzi MA,et al.C-Reactive protein levels in the first three hours afler acute cerebral infarction[J].Inter J Neur,2011,121(2):65-68.
  • 5Sepp D,Franz D,Triftshaeuser N,et al.Mobilization of CD133(+)progenitor cells in patients with acute cerebral infarction[J].PLoS One,2014,9(3):e70796.
  • 6Park SY,Kim J,Kim OJ,et al.Predictive value of circulating interleukin-6 and heart-type fatty acid binding protein for three months clinical outcome in acute cerebral infarction:multiple blood markers profiling study[J].Critical Care,2013,17(2):R45.
  • 7Kim SH,Lee JY,Park SH,et al.Plasma B-type natriuretic peptide level in patients with acute cerebral infarction according to infarction subtype and infarction volume[J].Int J Med Sci,2013,10(1):103-109.
  • 8Kuriyama N,Nagakane Y,Hosomi A,et al.Evaluation of factors associated with elevated levels of Platelet-Derived microparticles in the acute phase of cerebral infarction[J].Clinical and Applied Thrombosis-Hemostasis,2010,16(1):26-32.
  • 9Terruzzi A,Valente L,Mariani R,et al.C-reactive protein?and aetiological subtypes of cerebral infarction[J].Neurol Sci,2008,29(4):245-249.
  • 10Yokokawa H,Goto A,Terui K,et al.Prevalence of metabolic syndrome and serum marker levels in patients with four subtypes ofcerebral infarction in Japan[J].J Clin Neurosci,2008,15(7):769-773.

引证文献2

二级引证文献21

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部