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低甲状腺摄碘率甲亢的^(131)I治疗疗效分析 被引量:4

Radioiodine treatment of hyperthyroidism in patients with lowradioiodine thyroid uptake
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摘要 目的探讨甲状腺摄碘率<30%甲亢患者131I治疗疗效。方法分析甲状腺摄碘率<30%(实验组)及>30%(对照组)甲亢患者131I治疗后甲减发生率及甲亢治愈率。结果实验组276例与对照组568例甲亢患者131I治疗后6个月,治愈率与甲低发生率无明显差异。结论甲亢131I治疗不仅适合甲状腺摄碘率>30%的甲亢患者,同时适合甲状腺摄碘率<30%的甲亢患者。 Objective To analyze the effectiveness of radioactive 1311 in hyperthyroid patients with confirmed lower radio- iodine uptake as compared to patients with an uptake of over 30%. Methods We analyzed 276 consecutive hyperthyroid patients with a maxinaum iodine uptake of (24. 4± 5.3 ) % ( range, 20 ~ 30% ). The control group consisted of 568 patients treated with 13,1 with an iodine uptake of over 30%. Each patient was evaluated before and 6 months after treatment. Results By comparison of clinical remission of hyperthyroidism in patients presented with lower radioiodine to that of control patients, the overall success rate was not significantly different between these two groups ( P 〉 O. 05 ). Conclusion The results of the treatment of patients with a low iodine uptake are similar to the results obtained in the group of patients with iodine uptake above 30% and therelbre low iodine uptake should not be a contraindication for isotope 1311 therapy.
机构地区 核工业
出处 《四川医学》 CAS 2012年第12期2127-2128,共2页 Sichuan Medical Journal
关键词 甲亢 131I治疗 甲状腺摄碘率 hyperthyroidism low radioiodine uptake radioiodine therapy
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参考文献2

  • 1陆再英.内科学[M]北京:人民卫生出版社,2011718-719.
  • 2张永学.核医学[M]北京:科学出版社,2003262.

同被引文献23

  • 1谭天林.甲状腺功能亢进症术后复发的再手术治疗[J].中国耳鼻咽喉头颈外科,2006,13(2):83-84. 被引量:4
  • 2邹林菊,姚秋爱,陈舒婷,李莉.电话回访评价出院病人遵医行为的效果[J].护理研究(下旬版),2006,20(8):2236-2236. 被引量:56
  • 3Chen DY, Schneider PF, Zhang XS, et al. Striving for euthyroidism in radioiodine therapy of Graves' disease: a 12 - year prospective, randomized, open-label blinded end point study [J] . Thyroid, 2011 ,21(6) :647 -54.
  • 4WiIlegaignon J, Sapienza MT, Coura- Filho GB, et aL Graves' disease radioiodine-therapy: choosing target absorbed doses for therapy planning[J] . Med Phys,2014,doi:lO.ll18/1.4846056.
  • 5Enyi Ejeh MJ, Omotayo Ogunjobi K, Enyi Ejeh J, et al. Effectiveness of fixed dose radioactive Iodine for the treatment of hyperthyroidism: Experience of a teaching hospital in South West Nigeria [J] . Mo! Imaging Radionucl Ther ,2013 ,22(2) :36 -41.
  • 6] Bakos B, Takacs I, Nagy Z, et al. Long term efficacy of radioiodine treatment in hyperthyroidism [J] . Exp Clin Endocrino! Diabetes, 2013,121 (8) :494 -497.
  • 7Gibb FW, Zammitt NN, Beckett GJ. et al. Predictors of treatment failure, incipient hypothyroidism, and weight gain following radioiodine therapy for Graves' thyrotoxicosis [J] . J Endocrino! Invest, 2013 ,36(9) :764 -769.
  • 8Collier A. Thyrotoxicosis and radioiodine therapy: Does the dose matter? [J] . Indian J Endocrino! Metab, 2012, 16 ( 2 ) : 147 - 149.
  • 9闻捷馥,宋敏,于敬芝,李凤英,申玉梅.加强医患沟通 实施出院患者全员电话访谈[J].中国医院,2008,12(2):57-59. 被引量:6
  • 10李飞,司宏伟,岳峤,赵学峰,徐慧琴.Grave's病再次^(131)I治疗时间的选择[J].安徽医药,2011,15(1):46-48. 被引量:7

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