摘要
目的观察不伴黄斑水肿的重度非增生性糖尿病视网膜病变患者在行全视网膜光凝治疗前后黄斑中心厚度及视力的变化,探讨治疗的安全性。方法收集我院26例(52眼)不伴黄斑水肿的重度非增生性糖尿病视网膜病变(Non-proliferative diabetic retinopathy,NPDR)的2型糖尿病患者(视力≥0.8),行每周1次的全视网膜光凝(Panretinal pho-tocoagulation,PRP)治疗,分四期完成。记录术前、术后3、6个月视力(visual acuity,VA),并使用光学相干断层扫描(opticalcoherence tomography,OCT)检测黄斑中心厚度。结果 26例重度NPDR患者(52眼)中,行PRP术后3个月、6个月VA与术前比较无统计学意义(P>0.05),术后3、6个月黄斑中心凹厚度与术前比较,差异有统计学意义(P<0.05),PRP治疗后黄斑中心厚度较治疗前轻度增加。结论对不伴黄斑水肿的重度NPDR行PRP治疗安全有效,术后黄斑中心厚度轻度增加。
Objective To compare the thickness of fovea and visual acuity（VA） before and after panretinal photocoagu- lation（PRP） in patients with severe non-proliferative diabetic retinopathy（NPDR） without macular edema. Methods 26 patients with severe non-proliferative diabetic retinopathy without macular edema in type 2 diabetes （52 eyes） （ visual acuity ≥ 0. 8 ） were studied. 52 eyes of 26 patients underwent scatter PRP in four sessions. Thickness of fovea was measured by optical coherence tomography（ OCT）, and VA was measured before PRP and at the following 3 months, 6 months. Results During the 6 months observation period, there was no significant difference in VA. Central macular thickness was increased at 3,6 months after PRP compared with that before PRP（ P 〈0. 05 for each）. Conclusion PRP had no effect on patiehts with severe non-proliferative dia- betic retinopathy without maeular edema,althouth mild maeular thickening frequently persists.
出处
《四川医学》
CAS
2012年第12期2125-2127,共3页
Sichuan Medical Journal
关键词
糖尿病视网膜病变
黄斑水肿
视力
光学相干断层扫描
全视网膜光凝
diabetic retinopathy
macular edema
visual acuity
optical coherence tomography
panretinal photocoagulation
