摘要
目的应用速度向量成像技术分析高脂血症患者治疗前、后颈总动脉管壁运动特点。方法 30例高脂血症患者均给予阿托伐他汀治疗,于治疗前及治疗后3,6,12个月,应用速度向量成像软件分析患者左侧颈总动脉短轴切面4个侧壁(前壁、内侧壁、后壁、外侧壁)的收缩期最大速度、最大切向应变及最大切向应变率,并进行比较。结果治疗后3个月患者左侧颈总动脉外侧壁收缩期最大速度(1.89±0.21)×10-2 cm/s、最大切向应变(3.43±0.99)%、最大切向应变率(0.31±0.02)s-1明显高于治疗前(0.90±0.28)×10-2 cm/s,(1.80±1.04)%,(0.10±0.06)s-1(P均<0.05);治疗后6,12个月其他侧壁收缩期最大速度、最大切向应变、最大切向应变率也明显高于治疗前(P<0.05)。结论速度向量成像技术可较好地评价高脂血症患者治疗前、后颈总动脉的管壁运动特征,对防治心、脑血管疾病有指导意义。
Objective To investigate the characteristics of the carotid artery wall motion in patients with hyperlipidemia before and after treatment by using velocity vector imaging （VVI） technique. Methods Thirty patients with hyperlipidemia took atorvastatin for 12 months. The maximum velocity （Vmax）, maximum strain （Smax） and maximum strain rate （SRmax） of the anterior wall, internal wall, posterior wall and lateral wall of left short-axis section of carotid artery were measured with velocity vector imaging technique before treatment, and 3, 6 and 12 months after treatment, and were compared with another 30 healthy volunteers. Results The Vmax （（1. 89 ± 0. 21） × 10^-2 cm/s）, Smax （（3.43±0. 99）%） and SRmax （（0. 31±0. 02）s^-1） of lateral wall of left short axis section of carotid artery were significantly higher 3 months after treatment than those before treatment （Vmax （0. 90 ±0. 28）× 10^2 cm/s, Smax： （1.80±1. 04）%, SRmax： （0. 10±0. 06）s-1） （P〈0.05）. The Vmax, Smax and SRmax of anterior, internal and posterior wall of left short axis section of carotid artery were significantly higher 6 and 12 months after treatment than those before treatment （P〈 0.05）. Conclusion VV1 technique can evaluate the biomechanical characteristics of the carotid artery in patients with hyperlipidemia before and after treatment, which plays an important role in the prevention and therapy of cerebrovascular disease.
出处
《中华实用诊断与治疗杂志》
2013年第1期26-28,共3页
Journal of Chinese Practical Diagnosis and Therapy
关键词
高脂血症
阿托伐他汀
颈动脉
速度向量成像
应变
应变率
Hyperlipidemia
atorvastatin
carotid artery
velocity vector imaging
strain
strain rate
