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激素依赖型溃疡性结肠炎的治疗进展 被引量:21

The advance of treatment in steroid dependency ulcerative colitis
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摘要 炎症性肠病主要包括克罗恩病和溃疡性结肠炎,是一组以反复发作为特征的慢性炎症性肠道疾病。大约20%的溃疡性结肠炎是一种慢性活动性疾病,为了维持缓解症状,常常需要几个疗程的激素治疗。尽管溃疡性结肠炎患者用激素治疗在短期内可以控制症状,但是在激素减量期间或停止应用激素时,溃疡性结肠炎的症状会复发,这种情况被定义为类固醇激素依赖。本文就激素依赖型溃疡性结肠炎的治疗进展作一综述。 The inflammatory bowel disease, mainly consisting of erohn' s disease and ulcerative colitis, is characterized by persistent intestinal active disease often requiring several courses of systemic steroids in order to achieve remission, but followed by recurrence during alleviating dose or stopping administration. Although short term control of symptoms can be achieved with steroid treatment, this pattern of drug response, known as steroid-dependency. The advance of treatment in steroid dependency ulcerative colitis will be reviewed in the review.
出处 《胃肠病学和肝病学杂志》 CAS 2013年第1期95-98,共4页 Chinese Journal of Gastroenterology and Hepatology
基金 哈尔滨市科委青年科技创新人才基金(2018rfqys103)
关键词 炎症性肠病 激素依赖型溃疡性结肠炎 免疫抑制剂 干细胞治疗 英夫利昔 抗生素 Inflammatory bowel disease Steroid-dependency ulcerative colitis Immunosuppressives Stem cellbased therapy Infliximab Antibiotics
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