摘要
目的探讨枯草杆菌二联活菌颗粒联合茵栀黄口服液早期口服预防足月正常新生儿黄疸的效果。方法将剖宫产出生的生后第2天出现黄疸的足月正常新生儿120例随机分成干预组和对照组。干预组予以枯草杆菌二联活菌颗粒联合茵栀黄口服液口服,对照组不予任何药物口服。观察、检测并记录两组新生儿生后1～7 d经皮黄疸指数,同时记录严重黄疸的例数。结果干预组与对照组比较,生后第1天、第2天经皮黄疸指数差别无统计学意义(P>0.05),第3～7天经皮黄疸指数均明显下降,差异有统计学意义(均P<0.05);干预组严重黄疸(经皮黄疸指数≥15 mg/dl)发生率明显低于对照组,两组比较差异具有统计学意义(P<0.05)。结论早期予以枯草杆菌二联活菌颗粒联合茵栀黄口服液口服可减轻足月正常新生儿黄疸的程度,减少新生儿高胆红素血症的发生率,从而减少胆红素脑病的发生率。
Objective To investigate the clinical effect of Combined Bacillus Subtilis and Enterococcus Faecium Granules with Muhivitamines plus Yinzhihuang oral liquid in the prevention of jaundice in full term normal newborns. Methods A total of 120 Cesarean section neonates were randomly divided into intervention group and control group in which the jaundice appeared two days after the birth. The intervention group（n =60） was treated with Combined Bacillus Subtilis and Enterococcus Faecium Granules with Muhivitamines plus Yinzhihuang oral liquid and the control group（ n = 60） was not treated. The variation of percu-taneous jaundice from the first day to seventh day was observed. And the cases With severe jaundice were recorded. Results The difference in jaundice index between the first days and two days newborns was not significance （P 〉 O. 05 ）, but the jaundice index in the intervention group decreased significantly among 3 days to 7 days newborns（ P 〈 0.05 ）. The incidence of severe jaundice （transcutaneous jaundice index ≥ 15 mg/dl） in the intervention group was significantly lower than that in the control group, and the difference was statistically significant（P 〈 0.05）. Conclusion Early oral Combined Bacillus Subtilis and Enterococcus Fae-cium Granules with Muhivitamines plus Yinzhihuang oral liquid can reduce the jaundice in the full-term normal newborns, and the incidence of neonatal hyperbilirubinemia, thereby the incidence of bilirubin encephalopathy.
出处
《中华全科医学》
2013年第2期218-219,共2页
Chinese Journal of General Practice
关键词
黄疸
新生儿
干预
早期
Jaundice
Neonate
Early intervention
