摘要
目的观察硬膜外镇痛(PCEA)联合亚甲蓝局部注射用于肛管直肠疾病术后镇痛的临床效果。方法选择肛管直肠疾病手术的300例患者为研究对象,随机分成2组,治疗组150例使用术后硬膜外自控镇痛(PCEA)联合亚甲蓝注射液行肛周皮下浸润,对照组150例采取单纯硬膜外自控镇痛(PCEA)。2组分别于术后6,12,24,48,72,168 h对镇痛效果进行对比观察。结果硬膜外自控镇痛(PCEA)联合亚甲蓝注射液行肛周皮下浸润在长效镇痛方面明显优于对照组(P<0.01)。结论硬膜外镇痛(PCEA)联合亚甲蓝局部注射用于肛管直肠疾病术后镇痛效果显著。亚甲蓝浓度不应超过0.33%,一次局部用量不超过30 mg。
Objective To study the analgesia effects of patient-controlled epidural analgesia（PCEA） combined with perianal skin infiltration with methylene blue on postoperative anorectal disease. Methods 300 patients with anorectal disease were se-lected. They were divided into two groups randomly. PCEA combined with perianal skin infiltration with methylene blue was car-ried out in treatment group. PCEA was taken in control group. Analgesic effects were compared between treatment group and con-trol group after 6,12,24,48,72 and 168 hours after operation respectively. Results Long-term analgesia effects of treatment group were superior to control group（ P 〈 0.01 ）. Conclusion The postoperative analgesia effects of PCEA combined with peri-anal skin infiltration with methylene blue line were remarkable in anal diseases. It was suggested that concentration of methylene blue should not be more than O. 33% ,and that the dosage of local injection should not be more than 30 mg.
出处
《中华全科医学》
2013年第2期193-193,251,共2页
Chinese Journal of General Practice
关键词
肛肠疾病
亚甲蓝
罗哌卡因
硬膜外自控镇痛
Anorectal disease
Methylene blue
Ropivacaine
Patient-controlled epidural analgesia
