摘要
目的比较射频消融、氩氦刀冷冻治疗早期肝癌对近期肝功能的影响。方法回顾性分析2009年1月-2012年1月解放军第302医院射频消融、氩氦刀冷冻治疗早期肝癌患者各40例,治疗前肝功能正常,肝癌消融范围相等,观察治疗后第2天的肝功能变化。结果射频消融、氩氦刀冷冻治疗均可导致ALT、AST升高、CHE下降,氩氦刀冷冻治疗还可导致TBiL、ALP升高,与治疗前比较差异均有统计学意义(P<0.01)。两组治疗前后差值比较,氩氦刀冷冻治疗能显著升高ALT、ALP,与射频消融比较差异有统计学意义(P<0.01或P<0.05)。结论在消融范围相等情况下,氩氦刀冷冻治疗对近期肝功能的影响比射频消融更为显著。
Objective To evaluate effect of radiofrequency ablation（RFA） and cryotherapy on the short-term liver ruction in patients with early liver cancer. Methods Patients with early liver cancer and normal liver function were treated with RF（ n = 40） or eryotherapy（ n =40） from January 2009 to January 2012. The liver function before and 2 days after the treatment were an- alyzed comparatively. Results Both RF and cryotherapy could result in high alanine aminotransferase（ALT） and aspartate amin- otransferase （ AST）, and low cholinesterase （ CHE）, P 〈 0.01. Total bilirubin （TBiL） and alkaline phosphatase （ALP） were ele-vated after CST（ P 〈 0.01 ）. And after treatment, ALT and ALP were significantly elevated after cryotherapy than RF（ P 〈 0.01 or P 〈 0.05 ）. Conclusion Under the same ablation range,liver function damage after cryotherapy was more severe than RF treat-merit.
出处
《中华全科医学》
2013年第2期183-184,共2页
Chinese Journal of General Practice
关键词
射频消融
氩氦刀
肝癌
肝功能
Radiofrequency ablation
Argon-helium cryotherapy
Liver cancer
Liver function
