摘要
目的对比分析人类免疫缺陷病毒(HIV)抗体不同检测模式的检测效果。方法采用两种检测模式对每一份血液标本进行HIV抗体初筛检测,对比分析两种组合模式的检测结果的阴、阳性,由HIV确证实验室对初筛阳性标本进行确认,并对两种组合模式的检测效果进行评价。结果在26 482例血液标本中,模式一初筛有31例阳性标本,阳性率为11.71/万,其中4份确认为阳性,其灵敏度和特异性分别为100%和99.90%;模式二初筛有40例阳性标本,阳性率为15.10/万,其中4份确认为阳性,其灵敏度和特异性分别为100%和99.86%。两种组合模式初筛检测HIV抗体的阳性率及其灵敏度和特异性差异均无统计学意义(P>0.05)。结论在进行HIV抗体初筛时,国产试剂组合模式可以替代进口试剂组合模式。
Objective To analyzed detection effects of different models of HIV antibody.Methods HIV antibody screening assay of blood samples were tested by two kinds of detecting methods,positive and negative of two kinds of combination detection results were comparatively analyzed,HIV confirmatory laboratory screening of positive samples were confirmed,and two kinds of combination detection effects were evaluated.Results In 26 482 blood samples,31 samples were positive,the positive rate was 11.71/million,of which 28 were confirmed as positive,the sensitivity and specificity were respectively 100.0% and 99.90%;40 positive samples were screened by second model,the positive rate was 13.59/million,of which 4 were confirmed as positive,its sensitivity and specificity were respectively 100.0% and 99.86%.Positive rates and its sensitivities and specificities of two kinds of combination screening for detection of HIV antibody were not statistically significant（P0.05）.Conclusion In HIV antibody screening,homemade reagent combination mode can replace imported reagent combination.
出处
《检验医学与临床》
CAS
2013年第2期173-174,共2页
Laboratory Medicine and Clinic
