摘要
目的 :探讨冬虫夏草对lgA肾病小鼠腹腔巨噬细胞功能的影响。方法 :将 30只BALB/c小鼠按体重随机分为正常对照组 ,模型组与虫草组 ,采用半体内法测定小鼠腹腔巨噬细胞吞噬鸡红细胞的能力 ,以吞噬百分率和吞噬指数作为腹腔巨噬细胞吞噬功能的指标。结果 :虫草组腹腔巨噬细胞吞噬百分率和吞噬指数均高于模型组 (P <0 .0 5) ,血清循环免疫复合物 (CIC)低于模型组 (P <0 .0 5)。结论 :冬虫夏草可以改善lgA肾病小鼠巨噬细胞吞噬功能 。
Objective:To study the effect of cordyceps sinensis on abdominal cavity phagocyte function of IgA nephropathy mouse.Methods:Thirty BALB/c mice are divided into control group,model group and Cordyceps Sinensis group (CS group) at random according to body weight,observe the abdominal cavity phagocyte phagocytosing red blood cell of hen,phagocytic percentage and index are used to estimate phagocyte function.Results:Phagocytic percentage and index of CS group are higher than that of model group(P<0.05),circulating immune complex(CIC) is lower than that of model group(P<0.05),IgA immune fluorescence in mesengial area of glomerulus is weaker than that of model group.Conclusion:Cordyceps Sinensis can improve phagocyte function of IgA nephropathy mouse,decrease CIC and lessen IgA-IC deposition in mesengial area of glomerulus.
出处
《山东医科大学学报》
2000年第2期221-222,共2页
Acta Academiae Medicinae Shandong
关键词
冬虫夏草
肾小球肾炎
巨噬细胞功能
Drugs,Chinese herbal
Cordyceps Sinensis
Glomerulonephritis,IgA
Phagocytes
