摘要
目的:将富血小板纤维蛋白(Pl at el et-ri ch fi bri n,PRF)应用于牙槽嵴裂植骨手术,验证其是否能够减少植骨术后的骨吸收。方法:8～12月龄犬8只,以外科手术的方法制备双侧牙槽嵴裂模型,随机于两侧同期植入自体髂骨(对照组)及自体髂骨混合PRF(实验组)。于术后当日、2个月、4个月时拍摄上颌骨CT,利用三维重建软件测量植骨区体积,计算骨吸收率。结果:术后2个月、4个月时实验组的骨吸收率明显小于对照组,行配对样本的t检验,P<0.01。结论:将PRF加入自体髂骨进行骨移植修复犬的牙槽嵴裂,在术后4个月的时间范围内,可以减少术后的骨吸收。
Objective We grafted the platelet-rich fibrin （PRF） mixed with autogenous lilac bone in the alveolar cleft and evaluated the bone resorption after operation. Methods 8 dogs （8-12 months） were created bilateral alveolar cleft by surgical operation, autogenous lilac bone（control group） and the PRF mixed with autogenous lilac bone（PRF group） were implanted into the defect of one side randomly and bone regeneration was investigated 2 months and 4 months after implantation. Results The bone resorption of the PRF group was lower than that of the control group at 2 months and 4 months,P〈0.01. Conclusion Autogenous lilac bone grafting with PRF,which significantly reduces postoperative bone resorption on dog bilateral alveolar cleft model.
出处
《中国美容医学》
CAS
2013年第1期24-27,共4页
Chinese Journal of Aesthetic Medicine
关键词
富血小板纤维蛋白
牙槽嵴裂植骨
三维重建
骨吸收率
platelet-rich fibrin（PRF）
alveolar bone grafting
three-dimensional reconstruction
bone resorption
