摘要
目的了解医院呼吸科下呼吸道感染的病原菌分布及耐药性情况。方法收集呼吸科下呼吸道感染住院患者的痰标本,进行统计分析。结果检测出革兰阴性菌占71.8%,前三位分别是铜绿假单胞菌(29.3%)、鲍曼不动杆菌(13.5%)、肺炎克雷伯菌(10.5%);真菌占24.4%,以白色念珠菌为主;革兰阳性菌中占3.8%,以金黄色葡萄球菌(2.6%)为主;药敏试验显示,革兰阴性菌中,亚胺培南耐药率最低,其次为阿米卡星;革兰阳性菌中,金黄色葡萄球菌对利奈唑胺、万古霉素无耐药,发现耐甲氧西林葡萄球菌(66.7%)。结论呼吸科细菌耐药现象严重,需要进一步规范抗生素的应用,减少耐药菌的产生。
Objective To investigate the pathogenic bacteria distribution and their drug resistance in patients with lower respirato- ry infection. Methods The sputum of all patients was collected and cultured, and then the sputum samples were analyzed. Results The results showed that gram-negative bacteria took up 71.8% , fungi 24. 4% and gram-positive bacteria 3.8%. The main kind of gram-nega- tive bacteria was pseudomonas aemginosa （29.3%）, followed by baumanii （ 13.5% ） and klebsiella pneumoniae （ 10. 5% ）. Fungi main- ly were candida albicans and gram-positive bacteria were staphylococcus aureus. Gram-negative bacteria showed the lowest resistance to imipenem, followed by amikacin. Staphylococcus aureus had no resistance to vancomycin and linezolid, but showed a certain resistance to meticillin sodium. Conclusion Most bacteria in patients with lower respiratory infection show a certain resistance to many antibiotics. Therefore, the rational use of antibiotics is very important for the containment of bacterial resistance.
出处
《临床肺科杂志》
2013年第3期443-445,共3页
Journal of Clinical Pulmonary Medicine
关键词
下呼吸道感染
病原菌
抗生素
耐药性
lower respiratory infection
pathogenic bacteria
antibiotics
drug resistance
