摘要
目的:观察孟鲁司特辅助治疗迁延性肺炎的临床疗效。方法:将79例迁延性肺炎患儿随机分成两组,对照组38例给予常规治疗,观察组41例在常规治疗的基础上加用孟鲁司特治疗,2～5岁每次4mg,6～14岁每次5mg,每天1次,持续用药至症状、体征消失。结果:观察组总有效率92.7%高于对照组的78.9%,两组比较差异有统计学意义(χ2=6.162,P<0.05);观察组咳嗽、喘息、肺部体征消失时间及胸片肺部影像好转时间均短于对照组(P<0.05)。结论:孟鲁司特钠辅助治疗迁延性肺炎有助于缩短病程,且不良反应小,可作为迁延性肺炎的辅助治疗药物。
Objective： To study the clinical efficacy of montelukast in the treatment of prolonged pneumonia. Methods： Seventy-nine children with prolonged pneumonia were randomly divided into two groups. One was the observation group （n=41） , the other was the control group （n= 38）. Each group received conventional therapy. Montelukast was added in the observation group, 2 -5 years old children took 4 mga time, 6 - 14 years old children took 5 mg a time, once a day. The improvement time of symptoms and physical signs in the observation group was observed. Results： The total effective rate of the observation group （92.7%） was higher than that of the control group （78.9%） , the difference was significant （X2= 6. 162, P〈0.05）. The time courses of recovery of cough, wheezing, pulmonary signs and the duration of chest X-ray lung images improvement in the observation group were shorter than those in the control group （ P〈0.05 ）. Conclusions ： It could shorten the duration of illness with montelukast in the treatment of prolonged pneumonia.
出处
《儿科药学杂志》
CAS
2013年第2期25-27,共3页
Journal of Pediatric Pharmacy
关键词
孟鲁司特
迁延性
肺炎
儿童
Montelukast
Prolonged
Pneumonia
Children
