摘要
目的:探索开始喂养时间、喂养频率等因素对新生儿早期母乳性黄疸发生发展的影响,并与生理性黄疸进行鉴别。方法:将血清胆红素水平异常增高的母乳喂养新生儿,根据其生后第6天是否好转及第14天黄疸是否完全消退分为生理性黄疸组和早期母乳性黄疸组。观察开始喂养时间、生后3d内每天喂养次数和排便次数、第一次排胎便及黄便的时间。检测生后24～48h胎便中胆红素含量。结果:共316例母乳喂养新生儿纳入研究,生后第6天血清胆红素>209μmol/L[(240±31)μmol/L]为早期母乳性黄疸组176例,<115μmol/L[(95±20)μmol/L]为生理性黄疸组140例。生后3d内生理性黄疸组和早期母乳性黄疸组喂养频率分别为(5.8±1.9)次/天和(3.7±1.8)次/天,第2天胎便胆红素含量分别为(22±5)mg/g和(9±6)mg/g,第一次排胎便及黄便的时间分别为(8±4)h、(52±16)h和(12±7)h、(65±17)h,两组比较差异均有统计学意义(P<0.05)。结论:喂养方法不当、喂养不足可致新生儿母乳性黄疸,对血清胆红素稍高于生理性黄疸的早期母乳性黄疸患儿,应提倡在严密观察下"按需哺乳"而非"高频率哺乳"。
Objective： To explore the effects of the time to start-feeding, feeding frequency and other factors on the development and occurrence of breast feeding jaundice （BFJ） , and to differentiate between physiological jaundice （PJ） and BFJ. Methods： According to whether the jaundice was improved on the sixth day after birth, or were subsided completely on the fourteenth days after birth, 316 breastfeeding neonates with high serum bilirubin were divided into group PJ （n= 140） and group BFJ （n= 176）. The start-feeding time, the frequencies of daily feeding and defecation in three days after start-feeding, the time of first meconium passage and first yellow stool were observed. Bilirubin concentrations in meeoniurl were detected 24 -48 hours after birth. Results： Six days after birth, serum bilirubin 〉209 ~mol/L [ （240_＋31） t^mol/Ll identified as breast milk jaundice group; 〈115 ~mol/L [ （95_＋20） Ixmol/L] identified as physiologic jaundice group. In physiological jaundice group and breast milk jaundice group, the feeding frequency within three days after birth was （5.8_＋ 1.9 ） and （3.7±1.8 ） times/day, respectively; the bilirubin concentrations in meeonium on the second day after birth were （22±5） mg/g and （9±6） mg/g, respectively; The time of first meconium passage and first yellow stool were （8±4）hours, （52±16） hours and （12 ±7 ）hours, （65± 17 ）hours. The differences between the two groups were statistically significant （P〈0. 05 ）. Conclusions： Improper feeding practices can cause breast milk jaundice in newborns. Neonates with breast feeding jaundice, whose serum bilirubin is slightly high, should be under close obse ＇ation of ＂breastfeeding on demand＂ rather than ＂high frequency of breast-feeding＂.
出处
《儿科药学杂志》
CAS
2013年第2期21-23,共3页
Journal of Pediatric Pharmacy
关键词
母乳喂养
黄疸
新生儿
Breast milk
Jaundice
Neonates
