摘要
目的探讨听力正常的耳鸣患者畸变产物耳声发射(DPOAE)的临床特点,了解畸变产物耳声发射在耳鸣患者中的应用价值。方法对160例听力正常伴耳鸣的患者设定为耳鸣组,进行DPOAE测试,同时对120例听力正常且无耳鸣健康者设定为对照组,进行DPOAE测试,对比两组检测结果。对耳鸣患者给予营养神经药物和改善内耳血液循环药物联合治疗3周后再次进行DPOAE测试,对比治疗前后结果。结果耳鸣组中,DPOAE测试在各频率点的检出率均显著低于健康对照组(P<0.05)。耳鸣组经过治疗后,耳声发射在高频段的反应幅值明显提高,与治疗前相比,差异具有统计学意义(P<0.05)。结论耳鸣的产生可能与耳蜗外毛细胞早期损伤导致的高频听力损失相关,DPOAE的检测可反映早期耳蜗病变并可作为耳鸣患者的一种客观检查方法。
Objective To explore the clinical characteristics of the distort product otoacoustic emission（DPOAE）in the tinnitus patients with normal hearing capability and its applied value.Methods DPOAE test was held in 160 tinnitus patients with the normal hearing capability and 120 healthy controls with the normal hearing capability and no tinnitus symptoms.The results were compared between two groups.The tinnitus patients were given nerve-nourishing medicine and vasodilator medicine for consecutive 3 weeks and then DPOAE test was performed again.The results before and after treatment were compared.Results In tinnitus group,the incidence of DPOAE in each frequency was significantly lower than that in healthy controls（P0.05）.After the treatment,the DPOAE reacting amplitudes in high frequency were obviously improved in the tinnitus patients（P0.05）.Conclusion The occurrence of the tinnitus may be relevant to the cochlear outer hair cell early injury-induced high frequency hearing loss,and DPOAE test can reflect the early stage cochlear injury and act as an objective method for detecting the tinnitus.
出处
《山西医科大学学报》
CAS
2013年第1期66-68,共3页
Journal of Shanxi Medical University
关键词
耳鸣
畸变产物耳声发射
内耳
tinnitus
distortion product otoacoustic emission（DPOAE）
inner ear
