摘要
目的评估踝臂指数(ABI)与冠状动脉粥样硬化性心脏病患者冠状动脉病变严重程度的关系。方法顺序入选2012-01～2012-03在西安交通大学第一附属医院心内科住院并行ABI测定、冠脉造影的患者458例,根据ABI测定结果将患者分为ABI≤0.4、0.41-0.90和0.91-1.40组,行冠状动脉病变发生率的比较。据冠状动脉造影结果进行Gensini评分,用Pearson相关分析、Logistic回归分析研究ABI与冠状动脉病变严重程度的关系。结果冠状动脉病变发生率在ABI≤0.4、0.41-0.90和0.91-1.40组分别为93%,75%,45%,组间比较有统计学差异(P<0.001);ABI与Gensini积分及冠脉病变数量呈显著负相关(r=-0.652,P=0.002;r=-0.518,P=0.003);Logistic回归分析提示校正高血压、糖尿病、吸烟、年龄、性别后,冠心病的患病风险随ABI的减低而增高(P<0.05)。结论 ABI值可预测冠状动脉病变的严重程度,ABI数值越低,冠状动脉血管病变程度越重。
Objective To evaluate the relationship between ankle brachial index（ABI）and the extent of coronary artery lesion.Methods A total of 458 patients were enrolled consecutively from January to March in 2012.They had both coronary angiography（CAG）and ABI data available.Patients were stratified into three groups based on ABI results：ABI≤0.4,0.41-0.90 and 0.91-1.40.The correlation between ABI and the extent of coronary artery lesion was analyzed.Results The incidences of coronary artery diseases were 93%,75% and 45% for patients with ABI≤0.4,0.41-0.90 and 0.91-1.40,respectively ABI showed a negative correlation with Gensini scoring（r=-0.652,P=0.002） and the number of coronary artery lesion（r=-0.518,P=0.003）.After adjustment for hypertension,diabetes,smoking status,age,gender,ABI was significantly correlated with coronary artery disease（P0.05）.Conclusion The results suggest that ABI value may predict the extent of coronary artery lesion.The more coronary arteries are involved,the lower ABI value is observed.
出处
《山西医科大学学报》
CAS
2013年第1期35-38,共4页
Journal of Shanxi Medical University
基金
国家自然科学基金资助项目(81270236)
关键词
踝臂指数
心血管疾病
冠状动脉病变
冠状动脉造影
ankle brachial index
cardiovascular disease
coronary artery lesion
coronary angiography
