摘要
目的比较肠内营养支持与肠外营养支持对急性重症胰腺炎(SAP)患者的临床疗效。方法 2008年6月1日至2011年6月1日收治的SAP患者48例,按照就诊顺序随机分配营养支持的方式,其中接受肠内营养支持(EN)的患者24例和肠外营养支持(PN)组24例。分析比较两组患者的一般资料,于营养支持2周后评估两组的营养状况、相关生化指标;同时比较局部和全身的并发症,病死率和治愈率等。结果给予营养支持后,与PN组比较,EN组血清白蛋白显著升高(35.92±5.31)g/L vs(29.02±4.68)g/L(P<0.01),白细胞明显降低(8.27±2.64)×109/L vs(10.89±3.16)×109/L(P<0.05);急性呼吸窘迫综合征(ARDS)和其他感染性并发症发生率EN组均低于PN组16.7%(4/24)vs 37.5%(9/24),P<0.01。结论肠内营养支持是治疗SAP的重要手段,在无绝对禁忌证的前提下,使用EN在改善营养状况、减少并发症等方面更有优势。
Objective To compare the clinical effect of enteral nutrition（EN） and parenteral nutrkion（PN） in the treatment of severe acute pancreatitis（SAP）. Methods There were 48 inpatients of SAP from June 1st, 2008 to June lst,2011 ,which were divided into EN group （24 cases） and PN group （24 cases） randomly by the order of visiting doctors. Analysis was conducted on the general situations, the efficacy of two weeks＇ treatment, including the improvement of nutrition, complications of the treatment, mortality rate and cure rate. Results After the nutritional support,contrast to PN group, EN group achieved better results, such as enhancement of serum albumin （35.92 ± 5.31） g/L vs （29. 02±4.68） g/L（ P〈0.01） ,reduction of white blood cell count（8. 27±2.64） × 10^9/L vs （10. 89± 3.16）× 10^9/L（ P 〈0. 05）,less occurrence of complications such as ARDS and infection （16.7% vs 37.5%, P 〈 0.01）. Conclusion As the major treatment of SAP,early EN support is more safe and effective to patients in condition without eontraindieations than PN support,and EN support shows advantages on melioration of nutrition and reduction of complications.
出处
《临床荟萃》
CAS
2013年第2期172-174,共3页
Clinical Focus
关键词
胰腺炎
急性坏死性
肠道营养
胃肠外营养
pancreatitis, acute necrotizing
enteral nutrition
parenteral nutrition
