摘要
目的探讨新生儿肺炎患儿心肌酶谱及心电图改变的临床意义。方法选取2009年7月～2011年10月笔者医院收治的120例足月新生儿肺炎患儿其中重症肺炎组40例,单纯性肺炎组40例,对照组(正常足月新生儿)40例,肺炎组治疗前、后及对照组均行肘静脉穿刺采血做心肌酶谱(AST、LDH、CK、CK-MB)及心电图检查。结果除AST、CK在单纯组急性期和对照组比较中P>0.05外,单纯组和重症组急性期心肌酶谱与对照组比较以及单纯组与重症组急性期比较明显升高,心电图有明显改变,差异有统计学意义(P<0.05);单纯性肺炎组和重症肺炎组急性期和恢复期比较心肌酶谱及心电图结果有统计学意义(P<0.01);肺炎组恢复期心肌酶谱及心电图恢复正常(P>0.05)。结论新生儿肺炎可发生心肌损害,早期心肌酶谱测定及心电图检查有助发现其心肌损害,具有临床指导意义。
Objective To analyze the clinical significance of myocardial enzymes and electrocardiogram in neonatal pneumonia. Methods Totally 120 eases of full - term newbones in the period from July 2009 to October 2011 in our hospital were determined. 80 cases of infants with pneumonia including 40 mild pneumonia and 40 severe pneumonia were studied. The myocardial enzymes （ AST, LDH, CK, CK - MB） via cubital vein puncture and electrocardiogram were assayed in 80 cases of neonatal pneumonia both in prior - treatment and post - treatment, and in 40 cases of healthy newborns. Results The level of myocardial enzymes were obviously increased in the group of mild pneumonia and severe pneumonia compared with the group of healthy newborns and in the group of mild compared with the group of severe pneumonia （ P 〈 0.05） except that AST and CK in the group of mild pneumonia compared with the group of healthy newborns that were gradually tended to be normal level after treatment. Electrocardiogram and myocardial enzymes were obvious anomaly between the group of mild pneumonia compared with the group of severe pneumonia and become normal after treatment. Conclusion Myocardial injury can occur in neonatal pneumonia. The early detection of myocardial enzymes and electrocardiogram can be used as a valuable monitoring index in clinical practice.
出处
《医学研究杂志》
2013年第1期175-177,共3页
Journal of Medical Research
关键词
心肌酶谱
心肌损害
新生儿肺炎
心电图
Myocardial enzymes
Myocardial injury
Neonatal pneumonia
Electrocardiogram
