期刊文献+

胃癌分子靶向治疗进展 被引量:3

暂未订购
导出
摘要 胃癌是全世界第2大致死性癌症,每年约有100万新增胃癌病例。尽管外科技术在不断发展以及临床诊断手段和化疗策略也在不断更新,进展期胃癌和胃一食管交界部癌(GEJ)患者的临床生存率依然普遍较差,全球范围内的5年生存率为7%~14%。晚期胃癌普遍存在的不良预后必然会导致新的治疗策略的出现,特别是新的分子靶向药物的不断开发。
出处 《医学研究杂志》 2013年第1期4-7,共4页 Journal of Medical Research
基金 国家自然科学基金资助项目(81072175 81102010) 上海市卫生局科研项目(2009113) 上海市重点学科建设项目(B905)
  • 相关文献

参考文献15

  • 1Saltz LB,Meropol NJ,Loehrer PJ. Phase Ⅱ trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor[J].Journal of Clinical Oncology,2004,(7):1201-1208.doi:10.1200/JCO.2004.10.182.
  • 2Alberts SR,Sargent DJ,Smyrk TC. Adjuvant mFOLFOX6 withor without cetuxiumab (Cmab) in KRAS wild-type (WT) patients (pts) with resected stage Ⅲ colon cancer (CC):results from NCCTG IntergroupPhase Ⅲ Trial N0147[J].Journal of Clinical Oncology,2010.18s.
  • 3Woell E,Greil R,Eisterer W. Oxaliplatin,irinotecan and cetuximab in advanced gastric cancer:Wrst results of a multicenter phase II trial (AGMT Gastric-2)[J].Journal of Clinical Oncology,2008.15.
  • 4Lordick F,Luber B,Lorenzen S. Cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric cancer:a phase Ⅱ study of the Arbeitsgemeinschaft Internistische Onkologie (AIO)[J].British Journal of Cancer,2010.500-505.
  • 5Dragovich T,McCoy S,Fenoglio-Preiser CM. Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas:SWOG0127[J].Journal of Clinical Oncology,2006.4922-4927.
  • 6Cortés-Funes H,Rivera F,Alés l. Phase Ⅱ of trastuzumab and cisplatin in patients (pts) with advanced gastric cancer (AGC)with HER2/neu overexpression/amplication[J].Journal of Clinical Oncology,2007.4613.
  • 7Jφrgensen JT. Targeted HER-2 treatment in advanced gastric cancer[J].Oncology(Basel),2010.26-33.
  • 8Wainberg ZA,Anghel A,Desai AJ. Lapatinib,a dual EGFR and HER2 kinase inhibitor,selectively inhibits HER-2-amplified human gastric cancer cells and is synergistic with trastuzumab in vitro and in vivo[J].Clinical Cancer Research,2010.1509-1519.
  • 9Bang YJ,Van Cutsem E,Feyereislova A. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junctioncancer (ToGA):a phase 3,open-label,randomised controlled trial[J].The Lancet,2010.687-697.
  • 10Jφrgensen JT. Targeted HER2 treatment in advanced gastric cancer[J].Oncology(Basel),2010.26-33.

同被引文献22

引证文献3

二级引证文献23

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部