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肾脏嗜酸细胞瘤的临床诊疗(附2例报告并文献复习)

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摘要 目的:探讨肾脏嗜酸细胞瘤的症状、影像、病理、治疗及预后,以提高对该病的诊疗水平。方法:回顾分析2011年3月~10月我院收治2例肾脏嗜酸细胞瘤患者的临床资料,结合文献复习并讨论。结果:2例肿瘤大小分别为3.0cm×4.0cm和1.5cm×2.0cm。1例行左肾部分切除术,另1例行后腹腔镜下根治性左肾切除术,术后病理回报均为肾脏嗜酸细胞瘤。镜检:肿瘤细胞圆形或类圆形,细胞均匀一致,呈腺泡状或管状排列,胞质内富含嗜酸性颗粒,肿瘤中心部可见玻璃样变性无细胞区;免疫组化:EMA(+)、Vimentin(-)。本组中1例细胞核有一定程度异形性,另1例细胞核异形性明显,呈低度恶性。术后分别随访14个月及6个月,未见肿瘤复发,转移。结论:肾脏嗜酸细胞瘤是一种良性肿瘤,在临床症状、体征及影像学方面无明显特异性表现,确诊须依靠组织病理学检查。治疗以保留肾单位手术为宜,针对某些伴发恶性可能的肿瘤,肾根治性切除术也是积极的,术后需密切随访。
出处 《临床泌尿外科杂志》 2013年第1期65-67,共3页 Journal of Clinical Urology
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