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不同浓度丙泊酚对肝缺血-再灌注后肝功能的影响 被引量:1

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摘要 目的探讨不同浓度的丙泊酚对肝叶切除术患者肝缺血-再灌注损伤肝功能的影响。方法随机抽取60例行肝叶切除术的肝癌患者,将其分为A、B、C、D四组,平均每组15例。分别采用设定血浆靶浓度为丙泊酚组(A组)2μg.L-1,丙泊酚组(B组)3.5μg.L-1,丙泊酚组(C组)5μg.L-1及无丙泊酚组(D组)进行麻醉。结果 3组使用丙泊酚对相关生理指标的影响程度与D组比较,差异有统计学意义,且采用浓度为大于3.5μg.L-1组与2μg.L-1丙泊酚组比较,差异有统计学意义。结论丙泊酚能保护肝脏缺血-再灌注后的肝功能,浓度>3.5μg.L-1丙泊酚麻醉临床效果最为理想。
出处 《医药导报》 CAS 北大核心 2013年第1期52-55,共4页 Herald of Medicine
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