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体外循环心脏手术中单种和联合血液保护效果比较 被引量:4

Effect comparison between single and multimodal blood conservation in cardiac surgery with CPB
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摘要 目的比较多种联合措施及单种措施对血液的保护作用效果。方法对辽宁医学院附属第一医院2009年1月~2011年12月间行体外循环心脏直视手术的84例患者的血液保护措施(氨甲环酸、止血颗粒、去氨加压素及冷沉淀)资料进行收集和整理,用SPSS17.0软件进行统计分析。结果氨甲环酸加用止血颗粒可降低胸腔引流量,再加去氨加压素不仅减少胸腔引流量,还减少部分血细胞丢失及血液制品的输入量。加用冷沉淀之后的联合血液保护措施可明显提高术后血细胞计数、减少术后引流量(P均<0.05),而且明显减少新鲜冰冻血浆和浓缩红细胞的输入量(P均<0.05)。结论多种联合措施比单种措施对血液的保护作用效果显著。 Objective To compare the effectiveness between single and muhimodal blood conservation. Methods Data related to 84 patients who had treated by blood conservative drugs in cardiac operation using CPB bad been recorded and analyzed by SPSS17.0 between Jan, 2009 and Dec, 2011 in first hospital affiliated to Liaoning medical college. Re- suits AH hemostasis added to tranexamic acid decreased chest drainage and desmopressin plus to these drugs not only re- duced drainage volume but also blood cell loss as well as blood products use. Cryopreeipitate in addition to these drugs as a blood conservative strategy significantly increased the blood cell counts and reduced chest drainage ( all P 〈 0.05 ) , FFP and cryoprecipitate use( all P 〈 0.05 ). Conclusion Muhidiseiplinary blood conservation is more effective than single strategy in blood conservation.
出处 《山东医药》 CAS 2013年第1期18-20,共3页 Shandong Medical Journal
关键词 体外循环 联合血液保护 单种血液保护 氨甲环酸 extracorporeal circulation muhimodal blood conservation single blood conservation tranexamic acid
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