摘要
研究了对羟基乙酸的合成新工艺进行。以质量浓度为20%的Ca(OH)2为催化剂,在10～30℃催化乙二醛分子内歧化反应得到羟基乙酸钙,反应时间约1h为宜。羟基乙酸钙再用硫酸酸化得到羟基乙酸,产率大于95%。利用硫酸钙沉淀的形成可以方便地去除金属钙离子,反应选择性好,工艺过程简捷。
A new synthetic technology of glycolic acid was studied. Calcium glycollate was synthesized by intramolecular disproportionation reaction from glyoxal with Ca（OH）2 as catalyst, while the mass concentration of Ca（OH）2 was 20% or so, the temperature was controlled between 10- 30℃ and re- action time was about 1 h. Glycolic acid was then obtained through acidification with H2SO4 and the yield was above 95 %. tate. The reaction has Meanwhile, Ca2＋ ion was easily removed through the form of CANO4 precipi good selectivity and simple process.
出处
《精细石油化工》
CAS
CSCD
北大核心
2013年第1期21-23,共3页
Speciality Petrochemicals
基金
湖北省自然科学基金(2010CDB11106)
武汉市科技攻关计划(201210321106)
关键词
乙二醛
氢氧化钙
歧化反应
羟基乙酸
glyoxal
calcium hydroxide
disproportionation reaction
glycolic acid
