摘要
本文报道了在人—鼠嵌合条件下用腺病毒免疫人淋巴细胞,即用新生期去胸腺小鼠作为培养人B淋巴细胞在接受腺病毒抗原激活过程中的临时宿主(人-鼠嵌合)。在其它培养条件一致的情况下,与体外培养相比,具有延长人B细胞寿命,增加其存活率,即增加致敏B细胞的数量及其活力的特点。
A new method of Adenovirus-primed human lymphocytes was reported in mouse-human chimera. Neonatally, thymeetomized mice were used as the temporary hosts (mouse-human chimera) for human lymphocytes during antigen priming. When compared with culture in vitro under the same cultural conditions the chimera can prolong the life-span of B cell, increase their survival rate and the ability of secretion of specific antibodies.
出处
《白求恩医科大学学报》
CSCD
1991年第5期97-99,共3页
Journal of Norman Bethune University of Medical Science
