摘要
目的研究氨基酸对羟基磷灰石的水热诱导。方法以丙氨酸与甘氨酸为添加剂，采用水热合成法，得到了棒状的羟基磷灰石纳米颗粒，并对样品进行X射线衍射（XRD）、傅里叶红外光谱（FTIR）、透射电子显微镜（TEM）的表征分析。结果氨基酸可以诱导羟基磷灰石的形成；此外，通过改变氨基酸的比例，可以降低羟基磷灰石中碳酸根离子对磷酸根离子的取代，并且影响羟基磷灰石的结晶度和分散度。结论通过加入氨基酸调控羟基磷灰石，为制备高结晶度、低碳酸根离子取代羟基磷灰石提供了思路。
Objective To investigate the preparation method of hydroxyapatite by amino acids induced hydrothermal technique. Methods The hydroxyapatite nanorods were obtained using alanine and glycine as templates by hydrothermal method. The samples were characterized by X-ray diffraction （XRD）, Fourier infrared spectroscopy （FTIR）, transmission electron microscopy （TEM）. Results The results showed that amino acids induced the formation of hydroxyapatite. Amino acids could affect crystallinity and dispersion of the formed hydroxyapatite. In addition, the substituent content of carbonate ions in hydroxyapatite was reduced by changing the ratio of amino acids. Conclusion Hydroxyapatite with high crystallinity and low carbonate ions can be prepared by hydrothermal method in the presence of amino acids.
出处
《国际生物医学工程杂志》
CAS
2012年第6期329-331,共3页
International Journal of Biomedical Engineering
基金
国家自然科学基金资助项目（31100677）
福建省自然科学基金资助项目（2010J05112）
福建省教育厅面上项目（JA10053）
福州大学科技基金资助项目（2011-XQ-18,022228）
福建省科技重大专项资助项目（2010NZ0001-1）
关键词
羟基磷灰石
氨基酸
取代
水热法
Hdroxyapatite
Amino acid
Substitution
Hydrothermal method
