摘要
目的探讨维生素D治疗支气管哮喘患者临床疗效。方法选取支气管哮喘患者200例,随机分为常规治疗组和常规治疗+维生素D治疗组,所有患者治疗前后均测定血清中IL-2、TNF-α浓度,并进行哮喘控制测试(ACT评分),比较治疗前后上述指标变化情况。结果常规治疗+维生素D治疗组患者血清IL-2、TNF-α水平较常规治疗组明显降低,ACT评分显示完全控制及部分控制患者比例明显高于常规治疗组,差异有统计学意义(P<0.05)。结论血清维生素D可以降低气道反应性,提高支气管哮喘治疗疗效。
【Objective】 To investigate the effects of Vitamin D in Bronchial asthma patients. 【Methods】 200 cases were randomly divided into routine treatment bronchial asthma group and conventional therapy plus vitamin D therapy group, 200 cases of bronchial asthma patients tested serum vitamin D, IL-2 and TNF-a concentration, and ACT scores before and after treatment. 【Results】 Conventional therapy plus vitamin D treatment group of patients serum IL-2, TNF alpha levels decreased significantly comparing with the conventional treatment group, ACT score showed complete control and control patients was significantly higher than the conventional treatment group, there was a significant difference （P 0.05）. 【Conclusion】 Vitamin D can reduce airway reactivity, enhance the treatment of bronchial asthma curative effect.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2012年第32期80-82,共3页
China Journal of Modern Medicine
关键词
支气管哮喘
维生素D
气道炎症
疗效
bronchial asthma
vitamin D
airway inflammation
effect
