摘要
目的观察脑状态指数(CSI)和Narcotrend指数(NTI)在全麻苏醒期的变化,探讨两者在预测全麻苏醒期意识恢复中的效能。方法选择腹腔镜胆囊切除术患者25例,术中靶控输注(TCI)丙泊酚和瑞芬太尼维持麻醉,效应室靶浓度(Ce)分别为2～3μg/ml和2～4ng/ml,维持CSI值在40～60。记录全麻苏醒期不同意识恢复水平(对刺激无反应、呼之睁眼、定向力恢复)的CSI、NTI和丙泊酚Ce的变化。结果 CSI、NTI、丙泊酚Ce与苏醒期意识水平变化显著相关,相关系数分别为0.89、0.92和-0.86(P<0.01)。CSI、NTI及丙泊酚Ce预测患者意识恢复水平的概率(PK)均大于0.8(P<0.01)。结论 CSI、NTI和丙泊酚Ce均能及时反映全麻苏醒期意识水平的变化。
Objective To compare cerebral state index （CSI） and narcotrend index （NTI） as predictive factors on consciousness recovery during the emergence of general anesthesia. Methods Anesthesia of twenty-five patients undergoing laparoscopic cholecystectomy were maintenanced with TCI of pmpofol （target concentrations： 2-3 pg/ml ） and remifentanil （target concentrations： 2-4 ng/ ml） to maintain CSI in the range of 40-60. The values of CSI, NTI and Ce of propofol were recorded at different levels of concious recovery （non-reaction to simulations, eyes opening and orientation recovery）. Results There were significant correlations between CSI, NTI and Ce of propofol and consciousness recovery during anesthesia emergence with the correlation coefficients of 0.89, 0. 92 and -0. 86, respectively （P〈0. 01）. Probability （PK） values of CSI, NTI and Ce of propofol for predicting consciousness recovery were more than 0. 8 （P〈0. 01）. Conclusion CSI, NTI and Ce of propofol may be used to predict consciousness recovery during the emergence of general anesthesia.
出处
《临床麻醉学杂志》
CAS
CSCD
北大核心
2012年第12期1181-1183,共3页
Journal of Clinical Anesthesiology
