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控释地诺前列酮栓应用于足月胎膜早破引产30例 被引量:8

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摘要 目的观察控释地诺前列酮栓与缩宫素应用于足月胎膜早破引产的疗效及护理比较。方法选择64例足月胎膜早破产妇,分为观察组(30例)和对照组(34例),分别采用控释地诺前列酮栓和小剂量缩宫素引产。结果观察组治疗后4 h,12 h Bishop评分上升幅度高于同时点对照组(P<0.05),平均临产时间明显短于对照组(t=2.43,P<0.05),阴道分娩率明显高于对照组(χ2=5.59,P<0.05)。两组产后出血量和新生儿窒息率比较,无明显统计学差异(t=0.29,χ2=0.40,P>0.05)。观察组有2例发生宫缩过度刺激,取出普贝生后缓解;对照组出现1例恶心呕吐,症状较轻,未予处理,自行缓解。两组均无严重药物不良反应。结论控释地诺前列酮栓用于足月胎膜早破引产的疗效明显优于传统缩宫素,且临产时间短,降低了剖宫产率,安全性较好。此外,正确掌握使用方法,严密观察产程,加强护理,是取得良好引产效果的重要措施。
出处 《中国药业》 CAS 2013年第1期71-72,共2页 China Pharmaceuticals
基金 2009年浙江省苍南县科技计划项目 项目编号:2009S40
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