摘要
本实验采用高压液相色谱仪,对48例肺心病病人及10例健康人进行了24h尿去甲肾上腺素(NE)的测定。病人及健康人尿中NE含量分别为232.2±109.93及178.07±80.97μmol 24h。病人组明显高于健康人。肺心病急发期及缓解期病人24h中NE含量分别为280.74±90.54及203.36±86.46μmol/L,急发期明显高于缓解期。文中分析了心肺功能、pH值、病程、某些药物及肾功能对NE含量的影响。讨论了NE含量变化与5-羟色胺的关系,对肺心病病理生理过程的影响及这类生物胺测定的临床意义。
HPLC fluorophotometry was used to assay urine noradrenaline (NE) in 48 cases with cor pulmonale and 10 normal subjects.The contents of NE in urine of the patients and normal cases within 24 h were 232.2 ± 109.32μmol/L and 178.07 ± 80.97μmol/L respectively. The content was obviously higher in the patients than in the normal subjects .During the period of acute exacerbation and remission, the contents of urine NE in the patients within 24h were 280.74 + 90.54μmol/L and 203.36 ± 86.64μmol/L respectively, the former being evidently higher than the latter.The influence of the disease upon urine NE, pH value, cardiopulmonary function was analysed. The sequence of NE content changes in the pahtological course of cor pulmonale was also discussed.
出处
《白求恩医科大学学报》
CSCD
1991年第4期375-377,共3页
Journal of Norman Bethune University of Medical Science
