摘要
目的探讨颅内压（intmcnranial pressure，ICP）持续监护对重型脑损伤患者临床治疗的指导意义。方法选取2011年1月至2012年9月于我院进行开颅手术及脑室外引流术的重型颅脑损伤患者108例，根据随机原则分为实验组和对照组，每组54例。实验组和对照组患者均采用止血、抗感染、脱水、神经营养等治疗。实验组：使用Codman颅内压监护仪对患者进行硬膜下的颅内压监护。对照组：对患者颅内压不进行检测，仅按照传统方法进行颅内压预测和治疗。结果实验组和对照组相比在甘露醇使用时间及用量、肾功能损害程度和电解质紊乱等并发症的发生率、预后评估等各方面差异明显，P〈0．05。结论使用颅内压监护可以明显提高重型颅脑损伤患者的临床疗效，值得推广。
Objective To explore the clinical significance of continuous intracranial pressure （ICP） mon- itoring for severe brain injury. Methods 108 patients with severe brain injury who had underwent craniotomy and external ventricular drainage during the period of January 2011 to September 2012 were randomly divided into study group and control group, 54 for each group. Both groups received hemostasis, infection control, dehydra- tion, and nutritional therapy for nerve. The study group received a Codman ICP monitor for subdural intracranial pressure monitoring. The control group only received conventional methods for prediction and treatment of ICP without ICP monitoring. Results There were significant differences between the study group and the control group in duration and dosage of mannitol use and incidence rates of complications including renal dysfunction and electrolyte disorders （P〈0.05）. Conclusions Intracranial pressure monitoring can significantly improve the clin- ical efficacy in patients with severe brain injury. It is worth popularizing.
出处
《国际医药卫生导报》
2013年第1期87-90,共4页
International Medicine and Health Guidance News
关键词
颅内压
重型脑损伤
颅内压监护
甘露醇
临床疗效
Intracranial pressure
Severe brain injury
Intracranial pressure monitoring
Mannitol
Clinical efficacy
