摘要
目的探讨10种罕见类型宫颈癌的临床病理特征和预后情况。方法收集2005年1月至2011年12月宫颈绒毛管状腺癌、印戒细胞癌、黏液腺癌、透明细胞癌、腺样囊性癌、宫颈恶性黑色素瘤、宫颈湿疣性癌、宫颈癌肉瘤、宫颈小细胞神经内分泌癌及非典型类癌这10种罕见类型的宫颈癌患者各1例,进行回顾性分析并随访,结合文献分析临床病理特征和预后特点。结果 10例罕见类型宫颈癌的主要临床表现为接触性或不规则阴道流血、宫颈赘生物或糜烂样改变;诊断主要依靠病理学检查,某些类型宫颈癌需结合免疫组化协助诊断;手术是治疗的主要方式,必要时辅以术前或术后放、化疗。随访截止于2012年6月,6例存活,3例死亡,1例失访。结论 10种罕见宫颈癌的临床特点与常见类型宫颈癌无异,但恶性程度及预后有所不同,应根据不同类型宫颈癌临床预后特点制定合适的治疗方案。
Objective To investigate the clinical feature, diagnosis, therapy and prognosis of 10 rare types＇ cervical carcino- ma. Methods From January 2005 to December 2011, clinical data about 10 patients with rare cervical carcinoma, including cervical villoglandular papillary adenoeareinoma, signet-ring cell carcinoma, muciuous adenocareinoma, clear cell adenocarciuoma, adenoid cystic carcinoma, malignant melanoma, verrucous carcinoma, earcinosareoma, small cell neuroendocrine carcinoma and atypical carei- noid were retrospectively analyzed, and a review was made of the literature to identify the clinical features and prognosis of these rare malignancies. Results Vaginal bleeding and erosion or florid lesions were observed in most of cases. Diagnosis was based on the pa- thology, and some of them had to combine with immunohistochemical staining. Operation was the major therapy, assisted by chemo- therapy or/and radiotherapy when necessary. Till June 2012, 6 patients were alive, 3 died and 1 lost to follow-up. Conclusion Ten rare types of cervical cancer present similar clinical feature, but different malignant degree and prognosis. The treatment should be based on clinical feature and prognosis.
出处
《临床肿瘤学杂志》
CAS
2012年第12期1112-1116,共5页
Chinese Clinical Oncology
基金
广西自然科学基金资助项目(2011jjC40005)
关键词
宫颈癌
临床特征
诊治
预后
Cervical carcinoma
Chnical features
Diagnosis and treatment
Prognosis
