摘要
目的了解和分析我院围手术期患者抗菌药物应用情况。方法回顾性随机抽取2010年1月至2011年12月我院住院患者手术病例321份,以卫生部颁发的《抗菌药物临床应用指导原则》为评价标准,对围手术期患者抗菌药物使用情况进行分析。结果围手术期抗菌药物使用率为98.13%(315/321),术前使用抗菌药物的病例占68.78%,在术前使用抗菌药物病例中术前0.5～2h使用的占80.35%,I、II及III类手术术后平均使用抗生素时间为3.5、4.3及6.8d。其中I、II手术病例以预防性用药为主,III类手术以治疗用药为主;I、II手术抗菌药物使用不合理性分别占35.31%与40.52%,III类手术抗菌用药不合理性占24.12%。结论围手术期抗菌药物普遍存在不合理现象,主要表现为用药选择不够严格、时机选择不当、用药剂量过大、疗程过长及联合用药不当等。医院应该加强抗菌药物的应用管理,有效降低手术切口的感染率和耐药性的发生率。
Objective To investigate the perioperative utilization of antibiotics and analyze its rationality.Methods A total of 321 medical records of surgery cases from Jan 2010 to Dec 2011 in our hospital were collected for review.Guiding Principle of the clinical application of antibacterials（issued by Ministry of Health） was used as criteria.Results The ratio of peroperative use of antibiotics was 98.13%（315/321）.68.78% patient received antibiotics before operation and in which 80.35% received antibiotics at 0.5-2h before operation.I,II and III incisions stood at 3.5,4.3 and 6.8 days,respectively.I and II incisions used antibiotics for preventive purpose,and III incisions often for treatment purpose.The rational use of antibiotics in I,II and III incisions was 65.31%,60.52% and 74.12%,respectively.Conclusion The utilizaion of antibiotics in our hospital is irrational characterized by irrational drug choice,improper medication timing,overdose,long course of treatmend and combined medication errors.The management on perioperative utilization of antibiotics remains to be strengthened.
出处
《中国医药指南》
2012年第36期417-418,共2页
Guide of China Medicine
关键词
围手术期
抗菌药物
分析
Perioperative period
Antibiotics
Analysis
