摘要
目的探讨糖皮质激素治疗各个不同类型重型肝炎的临床疗效。方法在综合治疗的基础上,治疗组加用激素,每日加用强的松60mg,每日清晨顿服,待总胆红素消退<170mmol/L,强的松逐渐减量,1周减量约5mg,以每日10mg维持,直至胆红素下降到正常2倍左右时渐停。结果治疗组好转率明显高于对照组,2组比较差异有显著性(P<0.01)。结论激素用于重型肝炎,可快速改善肝功能,疗效明显,副作用小。
Objective To discuss the clinical efficacy of glucocorticoids in the treatment of various types of heavy hepatitis.Method Based on combined therapy,the treatment group was added with hormone,plus prednisone 60mg daily,early morning meal service daily,prednisone tapered until the total bilirubin dissipated less than 170mmol/L,,which reduced about 5mg1 weeks,10mg daily for maintenance,and bilirubin decreased to normal about 2 times when the stop gradually.Results In the treatment group,the improvement rate was higher than the control group,there was significant difference between 2 groups(P0.01).Conclusion Hormone was used for severe hepatitis,can improve liver function,which has obvious curative effect,and little side effect.
出处
《中国医药指南》
2012年第36期258-259,共2页
Guide of China Medicine
关键词
糖皮质激素
重型肝炎
Glucocorticoid
Severe hepatitis