摘要
目的观察大株红景天注射液联合依达拉奉治疗急性脑梗死的临床疗效。方法将149例患有急性脑梗死的病人随机分为两组:对照组74例,在常规治疗基础上给予依达拉奉30mg静滴,2次/d,共4周;治疗组75例,在常规治疗基础上给予大株红景天注射液10mL静滴,1次/d,同时给予依达拉奉30mg静滴,2次/d,共4周。治疗后观察并比较患者的病死率、血液流变学、神经功能缺损情况、临床疗效以及不良反应等方面的差异。结果治疗组病死率为8.11%,较对照组降低,具有统计学差异(P<0.05);治疗组在提高临床疗效、降低神经功能缺损方面均优于对照组,具有统计学差异(P<0.05);两组血液流变学指标组内比较具有统计学差异(P<0.05);两组治疗过程中均未发生不良反应。结论大株红景天注射液联合依达拉奉治疗急性脑梗死可以降低病死率和神经功能损伤,在一定程度上提高了急性脑梗死的临床疗效。
Objective To observe the differences between pure Edaravone and Rhadiola extract injection combination with Edaravone for the acute cerebral infarction patients＇ therapeutic effect. Methods 149 cases cerebral infarction patients were randomly divided into Edaravone group and Rhadiola extract injection combination with Edaravone group. Based on the conventional treatment, Edaravone group was treated with Edaravone 30 mg by intravenous infusion 2 times a day for 4 weeks. At the same time the other group was treated with Rhadiola extract injection 10 mL by intravenous infusion 1 times a day and Edaravone for 4 weeks. All patients were observed and analyzed the differences in the fatality, the therapeutic effect score, the neurological deficit score and the adverse effects. Results Rhadiola extract injection combination with Edaravone is superior to pure Edaravone in the improvement of fatality （8.11%）, therapeutic effect score and decrease of neurological deficit score （P〈0.05）. After treatment, hemorheology indicators are better than them before treatment in two groups （P〈0.05）. Conclusion Rhadiola extract injection combination with Edaravone could improve the fatality, therapeutic effect and decrease the neurological deficit of the acute cerebral infarction patients.
出处
《当代医学》
2013年第3期7-9,共3页
Contemporary Medicine
关键词
大株红景天注射液
依达拉奉
急性脑梗死
临床疗效
Rhadiola extract injection
Edaravone
Acute cerebral infarction
Therapeutic effect
