摘要
目的探讨经肝动脉化疗栓塞术(TACE)联合射频消融(RFA)对原发性肝癌的治疗效果。方法回顾性分析2008年4月～2010年7月收治的72例肝细胞癌患者的临床资料,根据治疗方法分为TACE联合RFA组(30例)、TACE组(42例)。TACE联合RFA组行TACE联合RFA治疗,TACE组行单纯TACE治疗。两组治疗结束后通过随访、影像学检查及血液分析进行评价。结果 TACE组患者的肿瘤总缩小率和肿瘤完全坏死率分别为49.8%和23.8%,1、2年生存率分别为69.0%和42.9%。TACE联合RFA组的分别为76.6%、53.4%,86.7%和76.0%,TACE联合RFA组的生存率明显高于单纯TACE组(P<0.05)。结论 TACE联合RFA治疗原发性肝癌可以使病灶得到有效控制,减少肿瘤复发,显著提高生存率,延长患者的生存期。
Objective To investigate the effect of transcatheter hepatic arterial chemoembolization （TACE） combined with radiofrequency ablation （RFA） in treatment of hepatocellular carcinoma. Methods A retrospective analysis was pertbrmed of 72 patients with hepatocellular carcinoma who received different treatments during April 2008-July 2010. The patients were divided into 2 groups： 30 patients in TACE ＋ RFA group, and 42 patients in TACE group. All patients were analyzed after treatment by follow-up, imaging examine and their blood biochemical tests. Results The rate of tumor shrinkage and necrosis was 49.8% and 23.8%,the survival rate in 1,2years were 69.0% and 42.9%, while the TACE＋RFA group was 76.6%, 53.4%, 86.7% and 76.0%,respectively. The survival rates in the synthetic therapy group were significantly higher than in the TACE group （P〈0.05）. Conclusion TACE combined with RFA can control lesions enlargement and reduce recurrent ,significantly increase survival rate and survival period in patients with hepatocellular carcinoma.
出处
《当代医学》
2013年第3期5-7,共3页
Contemporary Medicine
关键词
肝癌
肝动脉
栓塞
治疗性
射频消融
Hepatic carcinoma
Hepatic artery
Embolization,therapeutic
Radiofrequency ablation
