摘要
目的了解真菌诱发医院感染的病原菌种类及其临床意义,为制定有效防治医院感染措施提供依据。方法对28例真菌诱发医院感染进行检验诊断,分析其病原菌种类、原发疾病、所用药物以及抗真菌治疗预后。结果真菌诱发医院感染占医院感染总病例数的11.43%;患者平均年龄(62.71±7.56)岁,年龄分布表明年龄较大的患者尤其是老年患者更易受到医院真菌感染的侵袭;原发疾病为呼吸系统疾病最为常见,占42.86%;患者的送检标本分离出真菌54株,最多的是白色假丝酵母菌,占68.52%;患者先前均使用过较大剂量的广谱高效抗菌药物,39.29%患者使用过肾上腺皮质激素药物,7.14%患者使用过免疫抑制剂;患者经确诊后均进行抗真菌药物治疗并均得到治愈。结论临床诊治中应合理用药,预防真菌诱发医院感染,并加强真菌感染的检验,正确诊断,及时治疗。
OBJECTIVE To find out the species of the fungi causing nosocomial infections and its clinical significance so as to effectiveuy prevent and control the nosocomial infections. METHODS The laboratory testing and diagnosis of 28 patients with fungi-induced nosocomial infections were performed, the species of the pathogens, the primary diseases,antibiotics used, and the prognosis were analyzed. RESULTS The patients with fungi-induced nosocomial infections accounted for 11.43% of the total number of cases; the median age of the patients was （62.71±7.56） years, the distribution of the age indicated that the older the patient was, the more susceptible the patients were prone to the infectionsl the most common primary diseases were respiratory diseases, accounting for 42.86%; totally 54 strains of fungi were isolated from the submitted specimens, among which Candida albicans accounted for 68.52%. Large doses of broad spectrum antimicrobial agents were previously used by all patients, adrenal cortex hormones drugs were used by 39.29% of the patients,immunosuppressive agents were used by 7.14% ; all patients were cured through antifungal drug therapy after the diagnosis. CONCLUSION It is necessary for the hospital to reasonably use antibiotics to prevent the fungi-induced nosocomial infections as well as to strengthen the laboratory testing of the fungal infections aiming at the correct diagnosis and timely treatment.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第2期470-472,共3页
Chinese Journal of Nosocomiology
关键词
医院感染
白色假丝酵母菌
检验诊断
临床意义
Nosocomial infections
Candida albicans
Testing and diagnosis
Clinical significance
