摘要
目的探讨如何规范清洁手术围手术期预防使用抗菌药物的方法,为其合理使用抗菌药物提供指导。方法采用回顾性调查方法对医院2011年5月和9月出院的507例清洁手术患者抗菌药物使用进行评价分析。结果临床药师干预后,清洁手术抗菌药物使用率从5月份的85.83%降至9月份的46.54%;品种选择合理率由5月份的53.30%升至9月份的88.43%;预防用药疗程合理率由5月份的38.68%升至9月份的58.68%;术前给药时机合理率由5月份的73.11%升至9月份的88.43%;平均用药时间由5月份的3.49d降至9月份的2.63d;普外科、心内科、心外科和神经外科9月份抗菌药物使用率降至<30.00%;介入手术抗菌药物使用率从5月份的93.18%降至9月份的17.57%;品种选择合理率由5月份的39.02%升至9月份的76.92%;术前给药时机合理率由5月份的21.95%升至9月份的84.62%;冠脉造影诊断术和冠脉造影支架植入术抗菌药物使用率降至0。结论临床药师干预清洁手术预防用药后,可以有效提高围手术期预防用药的水平。
OBJECTIVE To explore the standard method of perioperative prophylactic antibiotics applied to clean surgery so as to guide the reasonable use of antibiotics. METHODS The antibiotic application of 507 patients who underwent the clean surgery from May and Sep 2011 was analyzed by retrospective investigation. RESULTS After clinical pharmacist intervention, among the clean surgical incision, the antibiotic utilization rate decreased from 85.83% in May to 46.54% in Sep; the rational ratio of antibiotic selection increased from 53. 30% in May to 88.43% in Sep% the rational ratio of course of antibiotic treatment increased from 38.68% in May to 58.68% of Sep; the rational ratio of administering opportunity before the operation increased from 73. 11% in May to 88.43% in Sep; the average application time decreased from 3. 49 days in May to 2. 63 days in Sep; all the antibiotic utilization rates, including department of genera/ surgery, department of cardiology, cardial surgery, and department of neurosurgery, were lower than 30. 00% in September. Among the intervention surgery cases, the antibiotic utilization rate decreased from 93.18% in May to 17.57% in Sep; the rational ratio of antibiotic selection increased from 39.02% in May to 76.92% in Sep; the rational ratio of administering opportunity before the operation increased from 21.95 % in May to 84. 62% in Sep% the antibiotic utilization rates of coronary angiography and stenting of coronary angiography decreased to 0. CONCLUSION The intervention of clinical pharmacists to the prophylactic antibiotic application can effectively improve the level of prophylactic use of antibiotics during perioperative period.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第2期435-437,共3页
Chinese Journal of Nosocomiology
关键词
临床药师
清洁手术
介入手术
抗菌药物
Clinical pharmacist
Clean surgery
Intervention surgery
Antibiotics
